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Invitrogen
GPR43 Polyclonal Antibody
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Product Details
PA5-32767
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 16 amino acid peptide from C-terminus of human GPR43.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
50 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Monkey (94%).
For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. GPCR GPR43 is a member of this family (subfamily carboxylic acid). It expression has been reported primarily in immune cells including monocytes and neutrophils. An EST has been isolated from a human pancreatic library.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: fatty acid receptor 2; free fatty acid activated receptor 2; Free fatty acid receptor 2; G-protein coupled receptor 43
Gene Aliases: FFA2; FFA2R; FFAR2; GPCR43; GPR43
UniProt ID: (Human) O15552
Entrez Gene ID: (Human) 2867
leukocyte chemotaxis involved in inflammatory response
immune system process
mucosal immune response
regulation of acute inflammatory response
positive regulation of cytokine production involved in immune response
cell surface pattern recognition receptor signaling pathway
positive regulation of acute inflammatory response to non-antigenic stimulus
inflammatory response
signal transduction
G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
lipid storage
positive regulation of insulin secretion
positive regulation of chemokine production
positive regulation of interleukin-8 production
glucose homeostasis
fat cell differentiation
negative regulation of insulin secretion
cellular response to fatty acid
regulation of peptide hormone secretion
ligand-gated ion channel signaling pathway
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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