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Invitrogen
Phospho-STK38/STK38L (Thr444, Thr442) Polyclonal Antibody
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FIGURE: 1 / 6
Phospho-STK38/STK38L (Thr444, Thr442) Antibody (PA5-99570) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded Phospho-STK38 (Thr444, Thr442) in mouse kidney tissue sections. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with Phospho-STK38 (Thr444, Thr442) polyclonal antibody (Product # PA5-99570) using a dilution of 1:200 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
Product Details
PA5-99570
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human STK38(Accession Q15208), corresponding to amino acid residues around phosphorylated Thr444.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
sequential chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of NDR1/2 only when phosphorylated at Thr444/442.
Target Information
This gene encodes a member of the AGC serine/threonine kinase family of proteins. The kinase activity of this protein is regulated by autophosphorylation and phosphorylation by other upstream kinases. This protein has been shown to function in the cell cycle and apoptosis. This protein has also been found to regulate the protein stability and transcriptional activity of the MYC oncogene. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ndr Ser/Thr kinase-like protein; NDR1 protein kinase; NDR2 protein kinase; nuclear Dbf2-related 2; Nuclear Dbf2-related kinase 1; Nuclear Dbf2-related kinase 2; serine/threonine kinase 38-like; Serine/threonine-protein kinase 38; Serine/threonine-protein kinase 38-like; stk38; stk38l; unnamed protein product
Gene Aliases: 4930473A22Rik; 5830476G13Rik; 9530097A09Rik; AA617404; B230328I19; KIAA0965; NDR; NDR1; NDR2; Ndr54; RGD1564793; STK38; STK38L
UniProt ID: (Human) Q15208, (Human) Q9Y2H1, (Mouse) Q91VJ4, (Mouse) Q7TSE6
Entrez Gene ID: (Human) 11329, (Human) 23012, (Mouse) 106504, (Rat) 361813, (Mouse) 232533, (Rat) 691337
nucleotide binding
magnesium ion binding
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
kinase activity
transferase activity
mitogen-activated protein kinase kinase kinase binding
cadherin binding
metal ion binding
protein serine kinase activity
ubiquitin-like protein reader activity
histone reader activity
UFM1-modified protein reader activity
actin binding
transferase activity, transferring phosphorus-containing groups
molecular_function
non-receptor serine/threonine protein kinase
DNA damage checkpoint
chromatin organization
protein phosphorylation
cellular response to DNA damage stimulus
negative regulation of metabolic process
intracellular signal transduction
protein modification process
negative regulation of MAP kinase activity
postsynapse organization
negative regulation of autophagy
positive regulation of autophagy
regulation of cellular component organization
cellular protein modification process
phosphorylation
biological_process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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