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Product Details
A30969
Product Specifications
Species
Human
Expression System
Insect cells
Amino acid sequence
135-end
Tag
GST-tag
Molecular weight
82.3 kDa
Class
Recombinant
Type
Protein
Conjugate
Form
Liquid
Concentration
See Label
Purification
purified
Storage buffer
50mM tris HCl, pH 7.5, with 0.1mM PMSF, 0.25mM DTT, 0.1mM EDTA, 50mM NaCl, 10mM glutathione, 25% glycerol
Contains
no preservative
Storage conditions
-80° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Dry ice
Product Specific Information
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 µg, 10 µg and 20 µg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 µL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase.^M
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This ADCK3 recombinant human protein (156-end) was expressed in insect cells.^M
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The purified catalytic domain (135-end) of ADCK3 can be used in a number of different applications, but has been specifically validated for use with our LanthaScreen™ Kinase binding assay technology to identify novel kinase inhibitors. ADCK3 recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.^M
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• Validated for use with the LanthaScreen™ Eu Kinase Binding assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service^M
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Protein Form: Recombinant, Catalytic
Target Information
ADCK3 serine/threonine kinase is a mitochondrial protein similar to yeast ABC1 that is a member of the ADCK family. CABC1 encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: aarF domain containing kinase 3; aarF domain-containing protein kinase 3; Atypical kinase COQ8A, mitochondrial; Chaperone activity of bc1 complex-like; chaperone activity of bc1 complex-like, mitochondrial; chaperone, ABC1 activity of bc1 complex homolog; Chaperone-ABC1-like; Coenzyme Q protein 8A; coenzyme Q8 homolog
Gene Aliases: ADCK3; ARCA2; CABC1; COQ10D4; COQ8; COQ8A; PP265; SCAR9
UniProt ID: (Human) Q8NI60
Entrez Gene ID: (Human) 56997
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