Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Highest antigen sequence indentity to the following orthologs: Mouse (80%), Rat (80%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-57259. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure. DHX36 (DEAH box protein 36), also known as MLE-like protein 1 and RNA helicase associated with AU-rich element ARE (RHAU), belongs to RNA helicase of the DEAH family and may function in sex development and spermatogenesis. It is expressed in testis and is evolutionary conserved with true orthologs in almost all animal species. DHX36 plays a role in degradation and deadenylation of mRNAs containing in their 3'-UTR the consensus ARE sequence element. DHX36 is required for early embryogenesis.
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Protein Aliases: Asp-Glu-Ala-His; ATP-dependent DNA/RNA helicase DHX36; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 36; DEAD/H box polypeptide 36; DEAH (Asp-Glu-Ala-His) box polypeptide 36; DEAH box protein 36; DEAH-box protein 36; G4 resolvase-1; G4-resolvase 1; G4-resolvase-1; G4R1; MLE-like protein 1; probable ATP-dependent RNA helicase DHX36; RNA helicase associated with AU-rich element ARE; RNA helicase associated with AU-rich element protein
Gene Aliases: DDX36; DHX36; G4R1; KIAA1488; MLEL1; RHAU
UniProt ID: (Human) Q9H2U1
Entrez Gene ID: (Human) 170506
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