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          Disclaimer

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Proteins & Peptides ›
          • KSR2 Proteins
          The product (cat # {{productObj.productId}}) that you're looking for has been discontinued and replaced with {{productObj.replacementProductId}}. The product (cat # {{productObj.productId}}) that you're looking for has been discontinued. Please contact Technical Support with any questions.

          Invitrogen

          Human KSR2, GST Tag Recombinant Protein

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          Cite Human KSR2, GST Tag Recombinant Protein

          Product Details

          A30500

          Product Specifications

          Expression System

          Insect cells

          Class

          Recombinant

          Type

          Protein

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          See Label

          Storage conditions

          -80°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Dry ice

          Product Specific Information

          For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 µg, 10 µg and 20 µg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 µL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase.

          This KSR2 recombinant human protein (554-end) was expressed in insect cells.

          KSR2 recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.

          • Validated for use with the Z'-LYTE™ assay
          • Available in multiple pack sizes for convenient use
          • Also available in our SelectScreen Kinase Profiling Service

          Protein Form: Recombinant, Active, Catalytic

          The gene accession number for KSR2 is NP_775869.3.

          Target Information

          KSR2 serine/threonine kinase or kinase suppressor of Ras 2 specifically regulates the activity of MEKK3 and COT but not other members of the MAP3K family. KSR interacts with a regulatory Raf molecule in cis to induce a conformational switch of MEK, facilitating MEK's phosphorylation by a separate catalytic Raf molecule in trans. Blocks MAP3K8 kinase activity and MAP3K8- mediated signaling. Acts as a negative regulator of MAP3K3- mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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