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Invitrogen
Human PIM3, GST Tag Recombinant Protein
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Product Details
A30516
Product Specifications
Species
Human
Expression System
Insect cells
Amino acid sequence
Full length
Tag
GST-tag
Molecular weight
62.6 kDa
Class
Recombinant
Type
Protein
Conjugate
Form
Liquid
Concentration
See Label
Purification
purified
Storage buffer
50mM tris HCl, pH 7.5, with 10mM glutathione, 25% glycerol, 0.1mM PMSF, 0.25mM DTT, 150mM NaCl, 0.1mM EDTA
Contains
no preservative
Storage conditions
-80°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Dry ice
Product Specific Information
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 µg, 10 µg and 20 µg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 µL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase.
This PIM3 recombinant human protein (full length) was expressed in insect cells.
PIM3 recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.
• Validated for use with the Z'-LYTE™ assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service
Protein Form: Full Length, Recombinant, Active
The gene accession number for PIM3 is NP_663453.1.
Target Information
PIM3 serine/threonine kinase or PIM-3 oncogene belongs to a family of protooncogenes. PIM3 is expressed in hepatocellular carcinoma development and plays a main role in the proliferation of human hepatoma cell lines. PIM3 also expressed in human pancreatic cancer cells and phosphorylates BAD to block Bad-mediated apoptosis in human pancreatic cancer cell lines. PIM3 is widely expressed, with the exception of no expression observed in colon, thymus, and small intestine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: pim-3 oncogene; serine/threonine kinase Pim-3; Serine/threonine-protein kinase pim-3
Gene Aliases: pim-3; PIM3
UniProt ID: (Human) Q86V86
Entrez Gene ID: (Human) 415116
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