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Product Details
BMS302
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Molecular weight
16.5 kDa
Class
Recombinant
Type
Protein
Purity
>98% prior to addition of bovine serum albumin
Conjugate
Form
Lyophilized
Purification
purified
Storage buffer
PBS
Contains
no preservative
Storage conditions
4°C
Shipping conditions
Wet ice
Product Specific Information
Description: Recombinant TNF-beta is produced in E. coli. No differences in the biological activities between Recombinant TNF-beta and natural human TNF- beta. BMS302 is the 16 kDa form of the full length 18 kDa human TNF-beta protein and expresses identical bioactivity to that displayed by natural human TNF-beta.
Purity: >98% prior to addition of bovine serum albumin.
Molecular Weight: 16.5 kDa.
Target Information
TNF beta, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4 and psoriatic arthritis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: DAMA-25N12.13; LT-alpha; Lymphotoxin-alpha; TNF b; TNF beta; TNF superfamily, member 1; TNF β; TNF-beta; TNFbeta; TNFβ; tumor necrosis factor beta; tumor necrosis factor ligand 1E; Tumor necrosis factor ligand superfamily member 1
Gene Aliases: LT; LTA; TNFB; TNFSF1; TNLG1E
UniProt ID: (Human) P01374
Entrez Gene ID: (Human) 4049
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