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Innovative solutions for confident metabolite identification
In analytical development, accuracy and efficiency are critical, especially when it comes to identifying and characterizing drug metabolites. Thermo Fisher Scientific delivers integrated solutions designed to meet the evolving demands of metabolite ID workflows in both small molecule and biologic drug development.
From high-throughput detection to deep structural elucidation, our technologies support Simultaneous QUAntitation and Discovery (SQUAD), helping to streamline workflows, reduce ambiguity, and accelerate timelines. Whether you're working on early-phase studies or late-stage development, our platforms provide the sensitivity, specificity, and scalability required to deliver confident results.
Explore how our solutions can support your analytical goals, helping to ensure data integrity, regulatory readiness, and scientific insight at every step.
This workflow provides an integrated approach for high throughput identification and structural characterization of metabolites utilizing liquid chromatography-high resolution mass spectrometry and efficient data processing in Thermo Scientific Compound Discoverer Software.
An integrated LC-HRAM mass spectrometry and Thermo Scientific Compound Discoverer Software workflow enables high-throughput metabolite identification and structural characterization.
This workflow enables characterization of drug metabolites from in vitro incubations of drug compounds, and the utility of intelligently acquired MSⁿ fragmentation data for transformation site localization and soft-spot analysis.
MSⁿ data supports precise metabolite characterization, transformation site localization, and soft-spot analysis from in vitro studies.
Leveraging Thermo Scientific mass spectrometers, SQUAD workflows are enhanced by the unique hardware and software solutions of these platforms.
SQUAD analysis seamlessly combines discovery and targeted workflows into a single experiment, offering a more comprehensive and versatile solution.
For Research Use Only. Not for use in diagnostic procedures.