Adeno-Associated Virus (AAV) particles

AAV manufacturing solutions for gene therapy commercialization

The rapidly growing interest in AAV-based gene therapies has led to the need for more cost-effective and scalable AAV vector production platforms.

Thermo Fisher Scientific offers innovative products and services that are designed to help accelerate your gene therapy projects. With solutions that span the entire AAV production workflow, our aim is to provide exceptional products and expertise to help customers develop breakthrough therapies.

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Plasmid development and production

The first step of the AAV production workflow is large-scale plasmid production and purification for subsequent transfection into viral producer cells.

Plasmid production products

From DNA vector selection to large-scale production and purification, we have solutions to meet your needs.

Gene synthesis services

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AAV vector production

We offer both mammalian and insect suspension cell platforms optimized for AAV vector production and scalability.

AAV production systems

Bioprocessing liquids and cell culture media preparation

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Downstream processing and characterization

Following production of crude virus preparations, we offer a large range of solutions for downstream purification and characterization of final viral vector products.


Effective and scalable methods for a high-purity and high-yield AAV product is critical for commercial success. We offer high-performance, scalable purification and polishing resins for a broad range of serotypes.

POROS chromatography resins

Mixers, buffers and single-use solutions

Lot release and characterization research and development

To help ensure regulatory approval of the final AAV product, QC testing must be implemented. We offer rapid molecular methods for containment and impurity testing for common AAV production workflow targets.

Fill and finish development

Once the final product has been purified and has passed the necessary quality and release testing criteria for clinical use, it is ready for formulation, final fill and finish.

CRO and CDMO Services

Our cell and gene therapy CRO solutions support customers through the unique demands gene therapy clinical trials call for. The extensive breadth and depth of therapeutic and functional expertise have guided a diverse range of cell and gene therapy assets through the development pipeline.

Our Viral Vector Contract Manufacturing Services support clients from drug development to full-scale manufacturing. In addition to product release, stability testing, process and analytical qualification, and custom cell line engineering, we provide global quality compliance and regulatory support.

This link takes users to cell and gene therapy CRO services

Intended use of the products mentioned on this page vary. For specific intended use statements please refer to the product label.