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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • OBFC2B Antibodies

          OriGene

          OBFC2B Monoclonal Antibody (OTI1E11), TrueMAB™

          View all (11) OBFC2B antibodies
          Datasheet
          Protocols
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          Datasheet
          Protocols
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          Cite OBFC2B Monoclonal Antibody (OTI1E11), TrueMAB™

          • Antibody Testing Data (8)
          OBFC2B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          OBFC2B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 8

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          OBFC2B Antibody (CF504022) in IHC (P)

          Immunohistochemical staining of paraffin-embedded human breast tissue within the normal limits using anti-OBFC2B mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, TA504022) {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          OBFC2B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          OBFC2B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          OBFC2B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          OBFC2B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          OBFC2B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          OBFC2B Antibody in Western Blot (WB)
          OBFC2B Antibody in Western Blot (WB)
          OBFC2B Antibody in Flow Cytometry (Flow)

          Product Details

          CF504022

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:150
          -

          Flow Cytometry (Flow)

          1:100
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Mouse / IgG1

          Class

          Monoclonal

          Type

          Antibody

          Clone

          OTI1E11

          Immunogen

          Full length human recombinant protein of human OBFC2B produced in HEK293T cell.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Lyophilized

          Concentration

          1 mg/mL

          Purification

          Affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 8% trehalose

          Contains

          no preservative

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)

          Target Information

          Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: hSSB1; LP3587; Nucleic acid-binding protein 2; oligonucleotide/oligosaccharide-binding fold containing 2B; Oligonucleotide/oligosaccharide-binding fold-containing protein 2B; Sensor of single-strand DNA complex subunit B1; Sensor of ssDNA subunit B1; single strand DNA-binding protein 1; Single-stranded DNA-binding protein 1; SOSS complex subunit B1; SOSS-B1

          View more View less

          Gene Aliases: hSSB1; LP3587; NABP2; OBFC2B; SOSS-B1; SSB1

          View more View less

          UniProt ID: (Human) Q9BQ15

          View more View less

          Entrez Gene ID: (Human) 79035

          View more View less

          Function(s)
          single-stranded DNA binding protein binding enzyme binding C-rich strand telomeric DNA binding G-rich strand telomeric DNA binding nucleic acid metabolism protein
          Process(es)
          double-strand break repair via homologous recombination DNA repair cellular response to DNA damage stimulus mitotic cell cycle checkpoint response to ionizing radiation snRNA transcription from RNA polymerase II promoter regulation of telomerase activity establishment of protein localization to telomere positive regulation of telomere capping
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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