Antibodies that detect 5-Methylcytosine can be used in several scientific applications, including Dot blot, Methylated DNA Immunoprecipitation, Immunocytochemistry, Flow Cytometry and Western Blot. These antibodies target 5-Methylcytosine in Human samples. Our 5-Methylcytosine monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse, Rabbit and Sheep. Find the 5-Methylcytosine antibody that fits your needs. Choose from 1 of 10 5-Methylcytosine antibodies, which have been validated in experiments with 19 publications and 26 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications. View more
Methylation of DNA cytosine bases plays important roles in the regulation of gene transcription. It has been estimated that 60 to 90% of the cytosines in CpG dinucleotides are methylated. An increase in methyl-CpG correlates with transcriptional silencing for the whole chromosome especially in developmentally regulated genes. Methylation is believed to lead to transcriptional silencing by multiple mechanisms including alteration of transcription factor binding to promoters and alteration in chromatin structure.
5-mC; 5-meC; 5-Methyl-cytosine; 5mc; C5H7NO3
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