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DTX4 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. It functions as an ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4.
AI449438; BC044798; D930042H13; deltex 4 homolog; deltex 4 homolog (Drosophila); deltex 4, E3 ubiquitin ligase; deltex E3 ubiquitin ligase 4; deltex homolog 4; deltex4; DTX4; E3 ubiquitin-protein ligase DTX4; KIAA0937; LRRGT00037; Protein deltex-4; RING finger protein 155; RING-type E3 ubiquitin transferase DTX4; RNF155
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