Hepatocyte growth factor (HGF) is a member of the plasminogen subfamily of S1 peptidases. The inactive polypeptide formed upon translation undergoes cleavage to produce a 69 kDa alpha-chain and 34 kDa beta-chain. A disulphide bond between the two chains makes active HGF. HGF is secreted by mesenchymal cells and stimulates mitogenesis, cell motility, and matrix invasion. It is involved in cellular growth and morphogenesis in a wide variety of tissue types. In humans, HGF is present on chromosome 7.
DFNB39; F-TCF; fibroblast-derived tumor cytotoxic factor; Hepatocyte growth factor; hepatocyte growth factor (hepapoietin A; scatter factor); Hepatopoietin-A; HGFB; HPTA; lung fibroblast-derived mitogen; Scatter factor; SF
Please enter the information below and press OK to send your cart to Core Services for purchase.