CrkL Antibodies

Antibodies that detect CrkL can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA and Flow Cytometry. These antibodies target CrkL in Human, Mouse, Rat, Non-human primate and Hamster samples. Our CrkL polyclonal,... Antibodies that detect CrkL can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA and Flow Cytometry. These antibodies target CrkL in Human, Mouse, Rat, Non-human primate and Hamster samples. Our CrkL polyclonal, recombinant monoclonal, monoclonal and... Antibodies that detect CrkL can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA and Flow Cytometry. These antibodies target CrkL in Human, Mouse, Rat, Non-human primate and Hamster samples. Our CrkL polyclonal, recombinant monoclonal, monoclonal and recombinant superclonal antibodies are developed in Rabbit, Mouse and Goat. These antibodies have been verified by Cell treatment, Knockdown and Knockout to confirm specificity to CrkL. Find the CrkL antibody that fits your needs. Choose from 1 of 34 CrkL antibodies, which have been validated in experiments with 4 publications and 99 images featured in our data gallery.

Browse primary antibodies for... Antibodies that detect CrkL can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA and Flow Cytometry. These antibodies target CrkL in Human, Mouse, Rat, Non-human primate and Hamster samples. Our CrkL polyclonal, recombinant monoclonal, monoclonal and recombinant superclonal antibodies are developed in Rabbit, Mouse and Goat. These antibodies have been verified by Cell treatment, Knockdown and Knockout to confirm specificity to CrkL. Find the CrkL antibody that fits your needs. Choose from 1 of 34 CrkL antibodies, which have been validated in experiments with 4 publications and 99 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

The CRKL gene encodes the CRK-like protein, an adaptor protein that plays a crucial role in intracellular signaling pathways related to cell proliferation, differentiation, and migration. CRKL contains SH2 and SH3 domains that facilitate interactions with other signaling molecules, influencing multiple pathways such as the MAPK, PI3K, and STAT pathways. It is involved in processes like cytoskeleton reorganization and immune cell signaling, with significant implications for development and cancer. CRKL is notably associated with Philadelphia chromosome-positive leukemias, where it interacts with the BCR-ABL fusion protein, contributing to leukemogenesis. Additionally, dysregulation of CRKL can affect cardiovascular development, leading to congenital heart defects. Research into CRKL focuses on understanding its role in signal transduction and its potential as a therapeutic target due to its involvement in oncogenic and developmental pathways.

Synonyms

1110025F07Rik; AA589403; AI325100; CRK like proto-oncogene, adaptor protein; CRKL; crkl {ECO:0000312; crk-like protein; crk-like protein {ECO:0000250; Crkol; EMBL:AAH85865.1, ECO:0000312; OTTHUMP00000198539; RGD:1308531}; UniProtKB:P46109}; v-crk avian sarcoma virus CT10 oncogene homolog-like; v-crk sarcoma virus CT10 oncogene homolog (avian)-like; v-crk sarcoma virus CT10 oncogene homolog-like

CrkL Antibodies

Target Information

Synonyms

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