This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma.
CD307d; Fc receptor homolog 4; Fc receptor-like 4; Fc receptor-like protein 4; FcR-like protein 4; FCRH4; gp42; hIFGP2; IFGP family protein 2; IGFP2; Immune receptor translocation-associated protein 1; immunoglobulin superfamily Fc receptor; immunoglobulin superfamily Fc receptor, gp42; immunoglobulin superfamily receptor translocation associated 1; IRTA1