This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma.
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Protein Aliases: CD307d; Fc receptor homolog 4; Fc receptor-like 4; Fc receptor-like protein 4; FcR-like protein 4; FCRH4; gp42; hIFGP2; IFGP family protein 2; IGFP2; Immune receptor translocation-associated protein 1; immunoglobulin superfamily Fc receptor; immunoglobulin superfamily Fc receptor, gp42; immunoglobulin superfamily receptor translocation associated 1; IRTA1
Gene Aliases: CD307d; FCRH4; FCRL4; IFGP2; IGFP2; IRTA1
UniProt ID: (Human) Q96PJ5
Entrez Gene ID: (Human) 83417
Molecular Function: cell adhesion molecule