IMPACT Antibodies

Antibodies that detect IMPACT can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Immunoprecipitation. These antibodies target IMPACT in Human, Rat and Mouse samples. Our IMPACT polyclonal antibodies are developed in... Antibodies that detect IMPACT can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Immunoprecipitation. These antibodies target IMPACT in Human, Rat and Mouse samples. Our IMPACT polyclonal antibodies are developed in Rabbit and Mouse. Find the... Antibodies that detect IMPACT can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Immunoprecipitation. These antibodies target IMPACT in Human, Rat and Mouse samples. Our IMPACT polyclonal antibodies are developed in Rabbit and Mouse. Find the IMPACT antibody that fits your needs. Choose from 1 of 6 IMPACT antibodies, which have been validated in experiments with 1 publication and 13 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody... Antibodies that detect IMPACT can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Immunoprecipitation. These antibodies target IMPACT in Human, Rat and Mouse samples. Our IMPACT polyclonal antibodies are developed in Rabbit and Mouse. Find the IMPACT antibody that fits your needs. Choose from 1 of 6 IMPACT antibodies, which have been validated in experiments with 1 publication and 13 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

Translational regulator that ensures constant high levels of translation upon a variety of stress conditions, such as amino acid starvation, UV-C irradiation, proteasome inhibitor treatment and glucose deprivation. Plays a role as a negative regulator of the EIF2AK4/GCN2 kinase activity; impairs GCN1-mediated EIF2AK4/GCN2 activation, and hence EIF2AK4/GCN2-mediated eIF-2-alpha phosphorylation and subsequent down-regulation of protein synthesis. May be required to regulate translation in specific neuronal cells under amino acid starvation conditions by preventing GCN2 activation and therefore ATF4 synthesis. Through its inhibitory action on EIF2AK4/GCN2, plays a role in differentiation of neuronal cells by stimulating neurite outgrowth.

Synonyms

E430016J11Rik; Impact; Impact homolog; impact RWD domain protein; impact, RWD domain protein; imprinted and ancient gene protein; Imprinted and ancient gene protein homolog; protein IMPACT; RWD domain containing 5; RWDD5

IMPACT Antibodies

Target Information

Synonyms

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