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MLH1 Antibodies

Antibodies that detect MLH1 can be used in several scientific applications, including Immunohistochemistry, Western Blot, Immunocytochemistry, SDS-PAGE and ELISA. These antibodies target MLH1 in Human, Mouse, Rat and Non-human primate samples. Our MLH1 monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse and Rabbit. These antibodies have been verified by Knockout and Relative expression to confirm specificity to MLH1. Find the MLH1 antibody that fits your needs. Choose from 1 of 72 MLH1 antibodies, which have been validated in experiments with 30 publications and 194 images featured in our data gallery.

Browse primary antibodies for ... View more Antibodies that detect MLH1 can be used in several scientific applications, including Immunohistochemistry, Western Blot, Immunocytochemistry, SDS-PAGE and ELISA. These antibodies target MLH1 in Human, Mouse, Rat and Non-human primate samples. Our MLH1 monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse and Rabbit. These antibodies have been verified by Knockout and Relative expression to confirm specificity to MLH1. Find the MLH1 antibody that fits your needs. Choose from 1 of 72 MLH1 antibodies, which have been validated in experiments with 30 publications and 194 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

MLH1 is a DNA mismatch repair protein. The repair of mismatch DNA is essential to maintaining the integrity of genetic information over time. An alteration of microsatellite repeats is the result of slippage owing to strand misalignment during DNA replication and is referred to as microsatellite instability (MSI). These defects in DNA repair pathways have been related to human carcinogenesis. The importance of mismatch repair genes became apparent with the identification of the genetic basis for hereditary nonpolyposis colon cancer (HNPC). MSHS2 is involved in the initial cognition of mismatch nucleotides during the replication mismatch repair process. It is thought that after MSH2 binds to a mismatched DNA duplex it is joined by a heterodimer of MLH1 and PMSH, which together help facilitate the later steps in mismatch repair.

Synonyms

1110035C23Rik; AI317206; AI325952; AI561766; COCA2; colon cancer, nonpolyposis type 2; DNA mismatch repair protein Mlh1; DNA mismatch repair protein Mlh1-like protein; FCC2; hMLH1; HNPCC; HNPCC2; I79_014127; MGC5172; mismatch repair protein 1; MLH1; MLH-1; mutL homolog 1; mutL homolog 1 (E. coli); mutL homolog 1, colon cancer, nonpolyposis type 2; mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli); mutL protein homolog 1

Target Video

6320261401112

MLH1 antibodies from Thermo Fisher Scientific

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Learn more about MLH1 primary antibodies that can be used in Immunohistochemistry, Western Blot, Immunocytochemistry and SDS-PAGE in Human, Mouse, Rat and Non-human primate samples.