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Antibodies that detect TNF alpha can be used in several scientific applications, including Western Blot, ELISA, Flow Cytometry, Immunohistochemistry (Paraffin) and Immunocytochemistry. These antibodies target TNF alpha in Human, Mouse, Rat, Porcine and Non-human primate samples. Our TNF alpha monoclonal, polyclonal, recombinant monoclonal, recombinant polyclonal and cocktail antibodies are developed in Mouse, Rabbit, Rat, Armenian Hamster and Goat. These antibodies have been verified by Cell treatment and Neutralization to confirm specificity to TNF alpha. Find the TNF alpha antibody that fits your needs. Choose from 1 of 134 TNF alpha antibodies, which have been validated in experiments with 1574 publications and 841 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.
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TNF alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophage and bind to its receptors, TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. TNF alpha is involved in the regulation of immune cells, cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. TNF alpha exists as a multimer of two, three, or five noncovalently linked units, but shows a single 17 kDa band following SDS-PAGE under non-reducing conditions. Knockout studies in mice also suggested the neuroprotective function of TNF alpha, and has been observed to causes tumor necrosis when injected into tumor-bearing mice. Other functions of TNF-alpha include its role in the immune response to bacterial, viral, parasitic and certain fungal infections, as well as its role in the necrosis of specific tumors. TNF alpha causes cytolysis or cytostasis of certain transformed cells, being synergistic with interferon-gamma in its cytotoxicity. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer.
APC1 protein; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; TNFA; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; TNFSF2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor alpha precursor; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor necrosis factor-alpha precursor; tumor-necrosis factor; tumour necrosis factor
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500 µg
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100 µg
25 Tests
25 Tests
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500 µg
100 Tests
100 µg
100 µg
100 µg
25 Tests
100 µg
100 Tests
100 µg
100 Tests
25 Tests
25 Tests
25 Tests
500 µg
150 µL
500 µg
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100 µg
1 mg
500 µg
500 µg
500 µg
1 mg
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