UBE2W Antibodies

Antibodies that detect UBE2W can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA and Immunocytochemistry. These antibodies target UBE2W in Human, Rat and Mouse samples. Our UBE2W polyclonal and monoclonal antibodies are... Antibodies that detect UBE2W can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA and Immunocytochemistry. These antibodies target UBE2W in Human, Rat and Mouse samples. Our UBE2W polyclonal and monoclonal antibodies are developed in Rabbit and Mouse. Find the UBE2W antibody that fits... Antibodies that detect UBE2W can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA and Immunocytochemistry. These antibodies target UBE2W in Human, Rat and Mouse samples. Our UBE2W polyclonal and monoclonal antibodies are developed in Rabbit and Mouse. Find the UBE2W antibody that fits your needs. Choose from 1 of 7 UBE2W antibodies, which have been validated in experiments with 2 publications and 11 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody... Antibodies that detect UBE2W can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA and Immunocytochemistry. These antibodies target UBE2W in Human, Rat and Mouse samples. Our UBE2W polyclonal and monoclonal antibodies are developed in Rabbit and Mouse. Find the UBE2W antibody that fits your needs. Choose from 1 of 7 UBE2W antibodies, which have been validated in experiments with 2 publications and 11 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

UBE2W accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins, and catalyzes monoubiquitination. Further, UBE2W is involved in degradation of misfolded chaperone substrates by mediating monoubiquitination of STUB1/CHIP, leading to recruitment of ATXN3 to monoubiquitinated STUB1/CHIP, and restriction of the length of ubiquitin chain attached to STUB1/CHIP substrates by ATXN3. After UV irradiation, but not after mitomycin-C (MMC) treatment, acts as a specific E2 ubiquitin-conjugating enzyme for the Fanconi anemia complex by associating with E3 ubiquitin-protein ligase FANCL and catalyzing monoubiquitination of FANCD2, a key step in the DNA damage pathway. UBE2W In vitro catalyzes 'Lys-11'-linked polyubiquitination, and transfers ubiquitin in complex with RING/U-box type E3s that do not have active site cysteine residues to form thioester bonds with ubiquitin, and preferentially ubiquitinates the N-terminus of substrates, such as ATXN3, STUB1 and SUMO2.

Synonyms

6130401J04Rik; E2 ubiquitin-conjugating enzyme W; N-terminal E2 ubiquitin-conjugating enzyme; N-terminus-conjugating E2; probable ubiquitin-conjugating enzyme E2 W; UBC16; UBC-16; UBE2W; Ubiquitin carrier protein W; ubiquitin conjugating enzyme E2 W (putative); ubiquitin conjugating enzyme E2W (putative); ubiquitin-conjugating enzyme 16; ubiquitin-conjugating enzyme 2W; ubiquitin-conjugating enzyme E2 W; ubiquitin-conjugating enzyme E2 W-like; ubiquitin-conjugating enzyme E2W; ubiquitin-conjugating enzyme E2W (putative); ubiquitin-protein ligase W

UBE2W Antibodies

Target Information

Synonyms

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