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Proteintech
HELLS Polyclonal Antibody
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Product Details
11955-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
HELLS Fusion Protein Ag2558 (1-348 aa encoded by BC031004)
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Amount
45 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MFGSSEKET IELSPTGRPK RRTRKSINYS KIDDFPNELE KLISQIQPEV DRERAVVEVN IPVESEVNLK LQNIMMLLRK CCNHPYLIEY PIDPVTQEFK IDEELVTNSG KFLILDRMLP ELKKRGHKVL LFSQMTSMLD ILMDYCHLRD FNFSRLDGSM SYSEREKNMH SFNTDPEVFI FLVSTRAGGL GINLTAADTV IIYDSDWNPQ SDLQAQDRCH RIGQTKPVVV YRLVTANTID QKIVERAAAK RKLEKLIIHK NHFKGGQSGL NLSKNFLDPK ELMELLKSRD YEREIKGSRE KVISDKDLEL LLDRSDLIDQ MNASGPIKEK MGIFKILENS EDSSPECLF (1-348 aa encoded by BC031004 )
Target Information
This gene encodes a lymphoid-specific helicase. Other helicases function in processes involving DNA strand separation, including replication, repair, recombination, and transcription. This protein is thought to be involved with cellular proliferation and may play a role in leukemogenesis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: helicase, lymphoid specific; hells; LSH; Lymphocyte-specific helicase; Lymphoid-specific helicase; Proliferation-associated SNF2-like protein; Senescence Associated Long Non-coding RNA; similar to Mus musculus lymphocyte specific helicase mRNA with GenBank Accession Number U25691.1; SMARCA6; SWI/SNF2-related matrix-associated actin-dependent regulator of chromatin subfamily A member 6; SWI/SNF2-related, matrix-associated, actin-dependent regulator of chromatin, subfamily A, member 6; TBC1D12: TBC1 domain family, member 12; unnamed protein product
Gene Aliases: AI323785; E130115I21Rik; HELLS; ICF4; LSH; Lysh; Nbla10143; PASG; SALNR; SMARCA6; Tbc1d12; YFK8
UniProt ID: (Human) Q9NRZ9, (Mouse) Q60848
Entrez Gene ID: (Human) 3070, (Mouse) 15201, (Rat) 294071
double-strand break repair via homologous recombination
urogenital system development
kidney development
double-strand break repair
chromatin remodeling
methylation-dependent chromatin silencing
apoptotic process
heterochromatin assembly
pericentric heterochromatin assembly
negative regulation of apoptotic process
hypermethylation of CpG island
lymphocyte proliferation
cell division
chromosomal DNA methylation maintenance following DNA replication
cellular response to leukemia inhibitory factor
negative regulation of intrinsic apoptotic signaling pathway
DNA methylation
chromatin silencing
transcription, DNA-templated
regulation of transcription, DNA-templated
cell cycle
mitotic nuclear division
multicellular organism development
maintenance of DNA methylation
lymphocyte differentiation
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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