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Proteintech
C7orf30 Polyclonal Antibody
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Product Details
22838-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
C7orf30 Fusion Protein Ag18286 (1-234 aa encoded by BC012331)
Conjugate
Form
Liquid
Concentration
0.24 mg/mL
Amount
36 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MGPGGRVAR LLAPLMWRRA VSSVAGSAVG AEPGLRLLAV QRLPVGAAFC RACQTPNFVR GLHSEPGLEE RAEGTVNEGR PESDAADHTG PKFDIDMMVS LLRQENARDI CVIQVPPEMR YTDYFVIVSG TSTRHLHAMA FYVVKMYKHL KCKRDPHVKI EGKDTDDWLC VDFGSMVIHL MLPETREIYE LEKLWTLRSY DDQLAQIAPE TVPEDFILGI EDDTSSVTPV ELKCE (1-234 aa encoded by BC012331)
Target Information
Required for normal mitochondrial ribosome function and mitochondrial translation (PubMed:22238375, PubMed:23171548). May play a role in ribosome biogenesis by preventing premature association of the 28S and 39S ribosomal subunits (Probable). Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits (Probable). Addition to isolated mitochondrial ribosomal subunits partially inhibits translation, probably by interfering with the association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes (Probable). May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome (PubMed:22238376, PubMed:23171548). May function as a ribosomal silencing factor (Probable). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Mitochondrial assembly of ribosomal large subunit protein 1; unnamed protein product
Gene Aliases: C7orf30; MALSU1; mtRsfA
UniProt ID: (Human) Q96EH3
Entrez Gene ID: (Human) 115416
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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