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Proteintech
RPS3 Monoclonal Antibody (2G7H4)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
66046-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
2G7H4
Immunogen
RPS3 Fusion Protein Ag7515 (1-243 aa encoded by BC003137)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.12 mg/mL
Amount
168 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAVQISKKR KFVADGIFKA ELNEFLTREL AEDGYSGVEV RVTPTRTEII ILATRTQNVL GEKGRRIREL TAVVQKRFGF PEGSVELYAE KVATRGLCAI AQAESLRYKL LGGLAVRRAC YGVLRFIMES GAKGCEVVVS GKLRGQRAKS MKFVDGLMIH SGDPVNYYVD TAVRHVLLRQ GVLGIKVKIM LPWDPTGKIG PKKPLPDHVS IVEPKDEILP TTPISEQKGG KPEPPAMPQP VPTA (1-243 aa encoded by BC003137)
Target Information
WD repeat domain 5 (WDR5) is a member of the WD repeat protein family, which is involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. WDR5, also known as BIG-3, is expressed in the developing growth plate, accelerates chondrocyte and osteoblast differentiation in vitro, and regulates osteoblast differentiation during embryonic bone development. WDR5 interacts with the pluripotency factor Oct4/POU5F1 and is required for the efficient formation of induced pluripotent stem (iPS) cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 40S ribosomal protein S3; FLJ26283; FLJ27450; IMR-90 ribosomal protein S3; MGC87870; OTTHUMP00000229804; OTTHUMP00000229805; OTTHUMP00000229874; OTTHUMP00000229877; OTTHUMP00000229878; OTTHUMP00000229879; OTTHUMP00000229880; OTTHUMP00000229882; OTTHUMP00000229883; OTTHUMP00000229886; unnamed protein product
Gene Aliases: D7Ertd795e; Rs_3; S3; uS3
UniProt ID: (Human) P23396, (Rat) P62909, (Mouse) P62908
Entrez Gene ID: (Human) 6188, (Rat) 140654, (Mouse) 27050
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
damaged DNA binding
RNA binding
mRNA binding
structural constituent of ribosome
DNA-(apurinic or apyrimidinic site) lyase activity
endodeoxyribonuclease activity
protein binding
microtubule binding
tubulin binding
DNA N-glycosylase activity
enzyme binding
kinase binding
protein kinase binding
Hsp70 protein binding
oxidized purine DNA binding
oxidized pyrimidine DNA binding
ubiquitin-like protein conjugating enzyme binding
protein kinase A binding
iron-sulfur cluster binding
Hsp90 protein binding
small ribosomal subunit rRNA binding
supercoiled DNA binding
class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DNA-binding transcription factor binding
RNA polymerase II regulatory region sequence-specific DNA binding
macromolecular complex binding
DNA repair
base-excision repair
translation
cellular response to DNA damage stimulus
chromosome segregation
positive regulation of gene expression
negative regulation of translation
positive regulation of microtubule polymerization
negative regulation of protein ubiquitination
cellular response to reactive oxygen species
regulation of apoptotic process
negative regulation of DNA repair
positive regulation of DNA repair
positive regulation of transcription from RNA polymerase II promoter
spindle assembly
response to TNF agonist
cellular response to hydrogen peroxide
positive regulation of NIK/NF-kappaB signaling
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
positive regulation of base-excision repair
cellular response to nerve growth factor stimulus
positive regulation of DNA-templated transcription, initiation
positive regulation of apoptotic signaling pathway
cytoplasmic translation
positive regulation of protein complex assembly
positive regulation of interleukin-2 production
positive regulation of activated T cell proliferation
positive regulation of T cell receptor signaling pathway
cellular response to tumor necrosis factor
cytoplasmic translational initiation
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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