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Proteintech

RPS3 Monoclonal Antibody (2G7H4), CoraLite® 594

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Product Details

CL594-66046

Applications
Tested Dilution
Publications

Immunocytochemistry (ICC/IF)

1:50-1:500
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

2G7H4

Immunogen

Full length RPS3 protein.

Conjugate

CoraLite® 594 CoraLite® 594 CoraLite® 594

Excitation/Emission Max

593/614 nm

Form

Liquid

Concentration

2 mg/mL

Amount

200 µg

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 0.5% BSA, 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20°C, store in dark

Shipping conditions

Wet ice

Target Information

WD repeat domain 5 (WDR5) is a member of the WD repeat protein family, which is involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. WDR5, also known as BIG-3, is expressed in the developing growth plate, accelerates chondrocyte and osteoblast differentiation in vitro, and regulates osteoblast differentiation during embryonic bone development. WDR5 interacts with the pluripotency factor Oct4/POU5F1 and is required for the efficient formation of induced pluripotent stem (iPS) cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 40S ribosomal protein S3; FLJ26283; FLJ27450; IMR-90 ribosomal protein S3; MGC87870; OTTHUMP00000229804; OTTHUMP00000229805; OTTHUMP00000229874; OTTHUMP00000229877; OTTHUMP00000229878; OTTHUMP00000229879; OTTHUMP00000229880; OTTHUMP00000229882; OTTHUMP00000229883; OTTHUMP00000229886; unnamed protein product

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Gene Aliases: D7Ertd795e; Rs_3; S3; uS3

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UniProt ID: (Human) P23396, (Rat) P62909, (Mouse) P62908

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Entrez Gene ID: (Human) 6188, (Rat) 140654, (Mouse) 27050

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Function(s)
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding DNA binding damaged DNA binding RNA binding mRNA binding structural constituent of ribosome DNA-(apurinic or apyrimidinic site) lyase activity endodeoxyribonuclease activity protein binding microtubule binding tubulin binding DNA N-glycosylase activity enzyme binding kinase binding protein kinase binding Hsp70 protein binding oxidized purine DNA binding oxidized pyrimidine DNA binding ubiquitin-like protein conjugating enzyme binding protein kinase A binding iron-sulfur cluster binding Hsp90 protein binding small ribosomal subunit rRNA binding supercoiled DNA binding class I DNA-(apurinic or apyrimidinic site) endonuclease activity DNA-binding transcription factor binding RNA polymerase II regulatory region sequence-specific DNA binding macromolecular complex binding
Process(es)
DNA repair base-excision repair translation cellular response to DNA damage stimulus chromosome segregation positive regulation of gene expression negative regulation of translation positive regulation of microtubule polymerization negative regulation of protein ubiquitination cellular response to reactive oxygen species regulation of apoptotic process negative regulation of DNA repair positive regulation of DNA repair positive regulation of transcription from RNA polymerase II promoter spindle assembly response to TNF agonist cellular response to hydrogen peroxide positive regulation of NIK/NF-kappaB signaling positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage positive regulation of base-excision repair cellular response to nerve growth factor stimulus positive regulation of DNA-templated transcription, initiation positive regulation of apoptotic signaling pathway cytoplasmic translation positive regulation of protein complex assembly positive regulation of interleukin-2 production positive regulation of activated T cell proliferation positive regulation of T cell receptor signaling pathway cellular response to tumor necrosis factor cytoplasmic translational initiation
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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