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Alomone Labs, LTD
Frizzled-3 (FZD3) Polyclonal Antibody
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Product Details
AFR-023-25UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide (C)KVSSYHGSLHRSRDGR, corresponding to amino acid residues 581-596 of mouse Frizzled-3, Extracellular, C-terminus
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Amount
20 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: frizzled 3; frizzled 3, seven transmembrane spanning receptor; frizzled family receptor 3; frizzled homolog 3; Frizzled-3; Fz-3; FZD3; hFz3; mFz3; unnamed protein product
Gene Aliases: AU020229; D930050A07Rik; Fz-3; Fz3; FZD3
UniProt ID: (Human) Q9NPG1, (Mouse) Q61086
Entrez Gene ID: (Human) 7976, (Mouse) 14365, (Rat) 266715
establishment of planar polarity
neural tube closure
hair follicle development
positive regulation of neuroblast proliferation
signal transduction
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
nervous system development
response to xenobiotic stimulus
Wnt signaling pathway
neuron differentiation
midbrain development
cell proliferation in midbrain
non-canonical Wnt signaling pathway
post-anal tail morphogenesis
dopaminergic neuron axon guidance
serotonergic neuron axon guidance
inner ear morphogenesis
negative regulation of mitotic cell cycle, embryonic
response to electrical stimulus
canonical Wnt signaling pathway
Wnt signaling pathway, planar cell polarity pathway
sympathetic ganglion development
commissural neuron axon guidance
motor neuron migration
negative regulation of execution phase of apoptosis
midbrain morphogenesis
neuron migration
multicellular organism development
brain development
response to drug
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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