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Invitrogen
CD9 Monoclonal Antibody (MM2/57)
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FIGURE: 1 / 7
CD9 Antibody (AHS0902) in WB
The EMBO journal 2023 -
3 Figure Involvement of caspase-1 in ILV formation A, B Formation of Tsg101 puncta and co-localization with mtDNA. THP-1 cells transduced with Tsg101-mCherry (red) were stained with PicoGreen (green) and induced to undergo cell death (no death, pyroptosis, or apoptosis). Co-localization of mtDNA with Tsg101 was visualized using confocal microscopy (left). The number of cells expressing Tsg101 puncta (upper)... View More
Product Details
AHS0902
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rabbit
Published species
Human,
Mouse,
Pig,
Rat
Host/Isotype
Mouse
/ IgG2b, kappa
Class
Monoclonal
Type
Antibody
Clone
MM2/57
Immunogen
Human platelet glycoprotein
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS with 0.1% BSA
Contains
0.1% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and by neurons and glial cells in the peripheral nervous system. CD9 belongs to a family of membrane proteins termed tetraspanins which transverse the membrane four times. In pre B cells and platelets, CD9 antigen regulates cell activation and aggregation possibly through an association with the integrin CD41 / CD61 (GPIIb / GPIIIa). CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion, plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on the dendritic cell plasma membrane which is important for effective T cell stimulation. CD9 functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression plays a critical role in the suppression of cancer cell motility and metastasis. CD9 is also considered as metastasis suppressor in solid tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 5H9; 5H9 antigen; antigen CD9; BA-2/p24 antigen; BA2; BTCC-1p; CD9; CD9 antigen; CD9 antigen (p24); Cell growth-inhibiting gene 2 protein; GIG2; Leukocyte antigen MIC3; motility related protein-1; Motility-related protein; MRP-1; p24; sCD 9; sCD9; soluble CD 9; soluble CD9; Tetraspanin-29; Tetraspanin29; Tspan-29; unnamed protein product
Gene Aliases: BTCC-1; CD9; DRAP-27; GIG2; MIC3; MRP-1; TSPAN-29; TSPAN29
UniProt ID: (Human) P21926, (Mouse) P40240
Entrez Gene ID: (Rabbit) 100345844, (Human) 928, (Mouse) 12527
movement of cell or subcellular component
cell adhesion
single fertilization
fusion of sperm to egg plasma membrane
negative regulation of cell proliferation
paranodal junction assembly
nervous system development
cell proliferation
glial cell migration
oligodendrocyte development
myoblast fusion involved in skeletal muscle regeneration
cell differentiation
platelet activation
receptor internalization
sperm-egg recognition
cellular response to low-density lipoprotein particle stimulus
negative regulation of platelet aggregation
regulation of macrophage migration
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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