Search
Bioss
Phospho-RSK2 (Tyr529) Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
BS-3368R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic phosphopeptide derived from human RSK2 around the phosphorylation site of Tyr529.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
RPS6KA3 (RSK2) is a serine/threonine kinase that modulates many cellular processes including transcription, adhesion, growth, survival, and proliferation. RPS6KA3 contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in the gene have been associated with Coffin-Lowry syndrome (CLS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: 90 kDa ribosomal protein S6 kinase 3; epididymis secretory sperm binding protein; Insulin-stimulated protein kinase 1; ISPK-1; MAP kinase-activated protein kinase 1b; MAPK-activated protein kinase 1b; MAPKAP kinase 1b; MAPKAPK-1b; p90-RSK 3; pp90RSK2; ribosomal protein S6 kinase 2; Ribosomal protein S6 kinase alpha-3; ribosomal protein S6 kinase, 90kDa, polypeptide 3; Ribosomal S6 kinase 2; RPS6KA3; RSK-2; S6K-alpha-3; unnamed protein product
Gene Aliases: C130006E23; CLS; HU-3; ISPK-1; ISPK1; MAPKAPK-1b; MAPKAPK1B; MPK-9; MRX19; p90-RSK2; p90RSK3; pp90RSK2; Rps6ka-rs1; RPS6KA3; RSK; RSK2; S6K-alpha3; XLID19
UniProt ID: (Human) P51812, (Mouse) P18654
Entrez Gene ID: (Human) 6197, (Mouse) 110651
nucleotide binding
magnesium ion binding
protein kinase activity
protein serine/threonine kinase activity
ribosomal protein S6 kinase activity
protein binding
ATP binding
kinase activity
transferase activity
protein kinase binding
metal ion binding
protein serine kinase activity
transferase activity, transferring phosphorus-containing groups
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
protein modifying enzyme
skeletal system development
toll-like receptor signaling pathway
signal transduction
chemical synaptic transmission
central nervous system development
positive regulation of cell growth
response to lipopolysaccharide
intracellular signal transduction
TORC1 signaling
negative regulation of apoptotic process
regulation of translation in response to stress
positive regulation of cell differentiation
positive regulation of transcription from RNA polymerase II promoter
regulation of translation
protein phosphorylation
cell cycle
phosphorylation
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support