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Proteintech
RACK1, GNB2L1 Monoclonal Antibody (1E11A7), CoraLite® Plus 488
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Product Details
CL48866940100UL
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
1E11A7
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles, store in dark
Shipping conditions
Wet ice
Target Information
RACK1 (receptor for activated C kinase 1) was identified through its binding to various PKC isoforms. Its main function is to recruit PKC and various other proteins to specific locations to form multiprotein complexes, mediating various signal pathways. RACK1 is required for VANGL2 membrane localization and for PTK2/FAK1 phosphorylation and dephosphorylation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cell proliferation-inducing gene 21 protein; GNB2L1; guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1; guanine nucleotide binding protein beta polypeptide 2-like 1; Guanine nucleotide-binding protein subunit beta-2-like 1; Guanine nucleotide-binding protein subunit beta-like protein 12.3; HLC-7; Human lung cancer oncogene 7 protein; lung cancer oncogene 7; OTTHUMP00000223870; OTTHUMP00000223891; OTTHUMP00000223893; OTTHUMP00000223900; OTTHUMP00000223901; OTTHUMP00000223902; OTTHUMP00000223930; OTTHUMP00000223931; PIG21; proliferation-inducing gene 21; protein homologous to chicken B complex protein, guanine nucleotide binding; rack-1; Receptor for activated C kinase; Receptor for activated C kinase 1; Receptor of activated protein C kinase 1; receptor of activated protein kinase C 1; Small ribosomal subunit protein RACK1; unnamed protein product
Gene Aliases: Gnb2-rs1; GNB2L1; H12.3; HLC-7; HLC7; PIG21; RACK1
UniProt ID: (Human) P63244
Entrez Gene ID: (Human) 10399
RNA binding
protein kinase C binding
receptor binding
protein binding
enzyme activator activity
ion channel inhibitor activity
cysteine-type endopeptidase activator activity involved in apoptotic process
enzyme binding
protein phosphatase binding
protein serine/threonine kinase inhibitor activity
protein tyrosine kinase inhibitor activity
cyclin binding
receptor tyrosine kinase binding
signaling adaptor activity
SH2 domain binding
identical protein binding
protein homodimerization activity
ribosome binding
translation regulator activity
cadherin binding
BH3 domain binding
binding, bridging
positive regulation of protein phosphorylation
cytoplasmic translation
translation
regulation of translation
apoptotic process
gastrulation
negative regulation of gene expression
protein ubiquitination
negative regulation of translation
negative regulation of Wnt signaling pathway
negative regulation of cell growth
positive regulation of cell migration
positive regulation of protein complex assembly
negative regulation of protein binding
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
regulation of protein localization
positive regulation of Golgi to plasma membrane protein transport
positive regulation of apoptotic process
pigmentation
positive regulation of GTPase activity
negative regulation of smoothened signaling pathway
rhythmic process
negative regulation of phagocytosis
regulation of cell division
regulation of cell cycle
negative regulation of protein kinase B signaling
positive regulation of mitochondrial depolarization
cellular response to glucose stimulus
cellular response to growth factor stimulus
rescue of stalled ribosome
regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
negative regulation of endoplasmic reticulum unfolded protein response
negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide
regulation of establishment of cell polarity
positive regulation of gastrulation
negative regulation of translational frameshifting
positive regulation of intrinsic apoptotic signaling pathway
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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