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ITM2C Monoclonal Antibody (2E8G11), CoraLite® 594
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
CL594-60095
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
2E8G11
Immunogen
Recombinant Protein
Conjugate
CoraLite® 594
CoraLite® 594
CoraLite® 594
Excitation/Emission Max
593/614 nm
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Target Information
Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BRICHOS domain containing 2C; cerebral protein 14; hRPC.1050_D_4; integral membrane protein 3; ITM2C; similar to E25C and BRI; transmembrane protein BRI3; unnamed protein product
Gene Aliases: BRI3; BRICD2C; E25; E25C; ITM3
UniProt ID: (Human) Q9NQX7
Entrez Gene ID: (Human) 81618
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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