This gene encodes a predicted transmembrane protein containing two extracellular CUB domains followed by a low-density lipoprotein class A (LDLa) domain. A similar gene in mice encodes a protein that plays a critical role in spatial learning and memory by regulating the function of synaptic N-methyl-D-aspartic acid receptor complexes in the hippocampus. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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Protein Aliases: BCTL1; Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1; BTCL1; Neuropilin (NRP) and tolloid (TLL)-like 1; Neuropilin and tolloid-like protein 1
Gene Aliases: AI851453; BCTL1; BTCL1; C130005O10Rik; NETO1; RGD1566269
Molecular Function: apolipoprotein cell adhesion molecule enzyme modulator extracellular matrix protein hydrolase membrane-bound signaling molecule metalloprotease oxidase oxidoreductase protease receptor serine protease signaling molecule transfer/carrier protein transporter