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SLC6A9 Polyclonal Antibody
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Product Details
OSS00342W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from aa region 500-600 of human SLC6A9 conjugated to blue carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: SLC6A9.
Target Information
Slc6a9 is a glycine transporter (GlyTs) that belong to a family of high affinity Na+- and Cl-dependent neurotransmitter transporters proteins. There are two subtypes of glycine transporters; GlyT1 (Slc6a9) and GlyT2. Slc6a9 are predominantly located on glia within caudal brain areas. The amino acid glycine acts as an inhibitory neurotransmitter in the central nervous system. The protein encoded by the Slc6a9 gene is one of two transporters that stop glycine signaling by removing it from the synaptic cleft. Diseases associated with SLC6A9 include Glycine Encephalopathy With Normal Serum Glycine and Infantile Glycine Encephalopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: glycine transporter 1; glycine transporter variant 1a; GlyT-1; Sodium- and chloride-dependent glycine transporter 1; solute carrier family 6 (neurotransmitter transporter, glycine), member 9; Solute carrier family 6 member 9; unnamed protein product
Gene Aliases: GCENSG; GLYT-1; GLYT-1b; GLYT1; SLC6A9
UniProt ID: (Human) P48067, (Mouse) P28571, (Rat) P28572
Entrez Gene ID: (Human) 6536, (Mouse) 14664, (Rat) 116509
neurotransmitter uptake
neurotransmitter transport
amino acid transport
glycine transport
sodium ion transmembrane transport
positive regulation of hemoglobin biosynthetic process
regulation of synaptic transmission, glycinergic
glycine secretion, neurotransmission
positive regulation of heme biosynthetic process
transport across blood-brain barrier
glycine import across plasma membrane
transport
cation transmembrane transport
L-alpha-amino acid transmembrane transport
amino acid transmembrane transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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