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Invitrogen
Cyclophilin 40 Polyclonal Antibody
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.jpg?time=20220826?time=20220826 "Cyclophilin 40 Antibody (PA1-028) in WB")
Product Details
PA1-028
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Hamster,
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues S(42) G N P L V Y L D V D A N(54) C of mature human CyPD.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 1mg/mL BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
PA1-028 detects cyclophilin D (CyPD) in rat, hamster, canine, mouse, and human tissues.
PA1-028 has been sucessfully used in Western blot procedures. By Western blot, this antibody detects a ~15 kDa protein in rat liver and heart extract, and a ~37 kDa in rat brain extract.
The PA1-028 immunogen is a synthetic peptide corresponding to residues S(42) G N P L V Y L D V D A N(54) C of mature human CyPD. This peptide (Cat. # PEP-104) is available for use in neutralization and control experiments.
Target Information
This gene encodes a H1 histone binding protein that is involved in transporting histones into the nucleus of dividing cells. Multiple isoforms are encoded by transcript variants of this gene. The somatic form is expressed in all mitotic cells, is localized to the nucleus, and is coupled to the cell cycle. The testicular form is expressed in embryonic tissues, tumor cells, and the testis. In male germ cells, this protein is localized to the cytoplasm of primary spermatocytes, the nucleus of spermatids, and the periacrosomal region of mature spermatozoa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 40 kDa peptidyl-prolyl cis-trans isomerase; 40 kDa peptidyl-prolyl cis-trans isomerase D; cyclophilin 40; Cyclophilin D; Cyclophilin-40; Cyclophilin-related protein; Cyp 40; Cyp D; CYP-40; CYP-S1; cytoplasmic cyclophilin D; EC 5.2.1.8; MGC33096; Peptidyl-prolyl cis-trans isomerase D; peptidylprolyl isomerase D; peptidylprolyl isomerase D (cyclophilin D); PPIase; PPIase D; PPID; rotamase; Rotamase D; S-cyclophilin; SCYLP; testicular tissue protein Li 147; unnamed protein product
Gene Aliases: 4930564J03Rik; CYP-40; CYP40; CYPD; I79_011990; PPID; Ppidl; Ppif
UniProt ID: (Human) Q08752, (Mouse) Q9CR16, (Rat) Q6DGG0
Entrez Gene ID: (Dog) 475481, (Human) 5481, (Mouse) 67738, (Chinese hamster) 100752921, (Rat) 361967
negative regulation of transcription from RNA polymerase II promoter
protein folding
apoptotic process
protein transport
viral release from host cell
lipid particle organization
positive regulation of apoptotic process
positive regulation of viral genome replication
positive regulation of protein secretion
protein-containing complex assembly
cellular response to UV-A
protein peptidyl-prolyl isomerization
protein complex assembly
transport
regulation of apoptotic process
chaperone-mediated protein folding
response to oxidative stress
negative regulation of apoptotic process
regulation of mitochondrial membrane potential
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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