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Invitrogen
Cyclin A2 Polyclonal Antibody
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FIGURE: 1 / 5
Cyclin A2 Antibody (PA5-14173) in IHC (P)
Immunohistochemistry analysis of Cyclin A2 in formalin-fixed and paraffin-embedded human hepatocarcinoma. Samples were incubated with Cyclin A2 polyclonal antibody (Product # PA5-14173) which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Product Details
PA5-14173
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 51-84 amino acids from the N-terminal region of human Cyclin A (CCNA2)
Conjugate
Form
Liquid
Concentration
2 mg/mL
Amount
800 µg
Purification
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Cyclins are regulatory subunits of the cyclin-dependent kinases (cdks) and they control transition at different specific phases of the cell cycle. The temporal expression of cyclins is tightly regulated and subsequently plays a critical role in controlling the enzymatic activity of cdks. These cyclin / cdk complexes are essential for passage through specific stages in the cell cycle. In mammalian somatic cells, cyclin A is required for S phase and passage through G2-phase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CCNA2; Cyclin A; Cyclin-A; Cyclin-A2; unnamed protein product
Gene Aliases: CCN1; CCNA; CCNA2
UniProt ID: (Human) P20248
Entrez Gene ID: (Human) 890
G1/S transition of mitotic cell cycle
G2/M transition of mitotic cell cycle
regulation of DNA replication
transcription, DNA-templated
Ras protein signal transduction
organ regeneration
response to estradiol
response to glucagon
cellular response to platelet-derived growth factor stimulus
post-translational protein modification
cellular response to leptin stimulus
mitotic cell cycle phase transition
cell cycle G1/S phase transition
positive regulation of transcription, DNA-templated
positive regulation of fibroblast proliferation
cell division
cellular response to cocaine
cellular response to luteinizing hormone stimulus
cellular response to estradiol stimulus
cellular response to hypoxia
cellular response to nitric oxide
cochlea development
cellular response to insulin-like growth factor stimulus
positive regulation of DNA biosynthetic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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