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Invitrogen
TCP-1 theta Polyclonal Antibody
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Product Details
PA5-54318
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TCP-1 theta. Recombinant protein control fragment (Product #RP-91816).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Amount
5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: KVLTRDKRLV PGGGATEIEL AKQITSYGET CPGLEQYAIK KFAEAFEAIP RALAENSGVK ANEVISKLYA VHQEGNKNVG LDIEAEVPAV KDMLEAGILD TYLGKYWAIK LATNAAVTVL RVDQIIMAKP AGGPKPPSGK KDWDD
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
Target Information
TCP-1 theta is theta subunit of the CCT (chaperonin containing TCP1 complex) chaperonin molecule which is abundant in the eukaryotic cytosol and may be involved in the transport and assembly of the newly synthesized proteins. Molecular chaperones assist in the protein folding upon ATP hydrolysis and TCP-1 theta may play a role in the assembly of the BBsome, a complex that is involved in ciliogenesis regulating transport vesicles to the cilia. Further, TCP-1 theta is also involved in the folding of actin and tubulin. The intact CCT complex is composed of eight polypeptides in a double ring structure. CCT is important within cells in the folding of the VHL tumor suppressor protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CCT-theta; Cctq; Chaperonin containing T-complex polypeptide 1 subunit 8; chaperonin containing TCP1, subunit 8 (theta); chaperonin subunit 8 (theta); KIAA0002; Renal carcinoma antigen NY-REN-15; T-complex protein 1 subunit theta; TCP-1-theta; unnamed protein product
Gene Aliases: AI132397; C21orf112; CCT8; CCTQ; D21S246; KIAA0002; PRED71; Tcpq
UniProt ID: (Human) P50990, (Mouse) P42932
Entrez Gene ID: (Human) 10694, (Rat) 288305, (Mouse) 12469
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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