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Phospho-Acinus (Ser1180) Polyclonal Antibody
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FIGURE: 1 / 1
Phospho-Acinus (Ser1180) Antibody (PA5-64646) in WB
Western Blot analysis of Phospho-Acinus (Ser1180) was performed using A549 (A), HeLa (B), Jurkat (C), NIH3T3 (D), and H9C2 (E) PC12 (F) whole cell lysates. The membrane was probed with Phospho-Acinus (Ser1180) Polyclonal Antibody (Product # PA5-64646).
Product Details
PA5-64646
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human Acinus (Phospho-Ser1180)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 30% glycerol, 0.87% NaCl
Contains
0.01% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Phospho-Acinus (Ser1180) Polyclonal Antibody detects endogenous levels of Acinus only when phosphorylated at Ser1180.
Target Information
ACINUS (apoptotic chromatin condensation inducer in the nucleus) is an induced of chromatin condensation. ACINUS is cleaved by caspase-3 and an additional unknown protease generating a small active peptide, p17, which causes chromatin condensation in vitro when it is added to purified nuclei. ACINUS also induces apoptotic chromatin condensation in cells. ACINUS is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Acinus; Apoptotic chromatin condensation inducer in the nucleus; DKFZp667N107; functional spliceosome-associated protein 152; unnamed protein product
Gene Aliases: 2610036I19Rik; 2610510L13Rik; ACIN1; ACINUS; acinusL; acinusS; ACN; C79325; fSAP152; KIAA0670; mKIAA0670
UniProt ID: (Human) Q9UKV3, (Mouse) Q9JIX8
Entrez Gene ID: (Human) 22985, (Mouse) 56215, (Rat) 305884
mRNA processing
apoptotic process
RNA splicing
erythrocyte differentiation
apoptotic chromosome condensation
positive regulation of apoptotic process
positive regulation of monocyte differentiation
negative regulation of mRNA splicing, via spliceosome
positive regulation of defense response to virus by host
regulation of autophagy
regulation of apoptotic process
mitophagy in response to mitochondrial depolarization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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