Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:2,000 | View 8 publications 8 publications |
Immunohistochemistry (IHC) |
- | View 2 publications 2 publications |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:100-1:400 | - |
Immunocytochemistry (ICC/IF) |
1:50-1:500 | View 3 publications 3 publications |
Immunoprecipitation (IP) |
0.5-4.0 µg | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
PTPN23 Fusion Protein Ag0765 (420-619 aa encoded by BC004881) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.38 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.1% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: QEKLHLRFC YEAVVRHVEQ VLQRHGVPPP CKPLASASIS QKNHLPQDSQ DLVLGGDVPI SSIQATIAKL SIRPPGGLES PVASLPGPAE PPGLPPASLP ESTPIPSSSP PPLSSPLPEA PQPKEEPPVP EAPSSGPPSS SLELLASLTP EAFSLDSSLR GKQRMSKHNF LQAHNGQGLR ATRPSDDPLS LLDPLWTLNK T (420-619 aa encoded by BC004881)
Plays a role in sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) via its interaction with the ESCRT-I complex (endosomal sorting complex required for transport I), and possibly also other ESCRT complexes. May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HD-PTP; His domain-containing protein tyrosine phosphatase; Protein tyrosine phosphatase TD14; PTP-TD14; Tyrosine-protein phosphatase non-receptor type 23
Gene Aliases: AI462446; HD-PTP; HDPTP; KIAA1471; PTP-TD14; PTPN23
UniProt ID: (Human) Q9H3S7, (Mouse) Q6PB44
Entrez Gene ID: (Human) 25930, (Mouse) 104831, (Rat) 117552
Molecular Function:
membrane traffic protein
protein phosphatase
protein modifying enzyme
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