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7TM Antibodies
VPAC2, VIP Receptor 2 Polyclonal Antibody
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FIGURE: 1 / 7
VPAC2, VIP Receptor 2 Antibody (7TM0372N-IC) in IHC (P)
Immunohistochemical identification of VIP Receptor 2 in small intestine. Sections were dewaxed, microwaved in citric acid, and incubated with anti-VPAC2 (VIP Receptor 2) antibody (7TM0372N-IC) at a dilution of 1:100. Sections were then sequentially treated with biotinylated anti-rabbit IgG and avidin-biotin solution. Color was developed by incubation in 3-amino-9-ethylcarbazole (AEC) , and sections were cou... View More
Product Details
7TM0372N-IC
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide with sequence LQFHRGSRAQSFLQTETSVI corresponds to amino acids 419 - 438 of human VPAC2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
Dulbecco's PBS, pH 7.4
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The Vasoactive Intestinal Polypeptide Receptor 2 (VPAC2) is a member of a family of three G-protein coupled receptors which mediate VIP (vasoactive intestinal peptide) and PACAP (pituitary adenlyate cyclase activating peptide) function in a variety of tissues. Together, the VPAC1 and VPAC2 receptors compose a subtype of the VIP receptor. Expression of the VIP and PACAP receptors has been linked to the presence of human tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Helodermin-preferring VIP receptor; human VIP2 receptor was previously called 'helodermin-preferring VIP receptor'; transmembrane domains are located at positions: 637-696; 772-844; 880-948; 1003-1071; 1147-1209; 1243-1302.; Potential glycosylation sites are located at :334-336; 424-426; 436; PACAP type III receptor; Pacap type-3; PACAP-R-3; PACAP-R3; PACAP3; PACAPR-3; Pituitary adenylate cyclase-activating polypeptide type III receptor; Pvr3; SCZD16; tcag7.970; unnamed protein product; Vasoactive intestinal polypeptide receptor 2; vasopressive intestinal peptide receptor 2; VIP and PACAP receptor 2; VIP receptor subtype 2; Vip type-2 receptor; VIP-R-2; Vip-r2; Vip2 receptor; VPAC2 receptor; VPAC2R
Gene Aliases: C16DUPq36.3; DUP7q36.3; PACAP-R-3; PACAP-R3; VIP-R-2; Vip2; VIP2R; VIPR2; VPAC2; VPAC2R; VPCAP2R
UniProt ID: (Human) P41587, (Rat) P35000, (Mouse) P41588
Entrez Gene ID: (Human) 7434, (Rat) 29555, (Mouse) 22355
pituitary adenylate cyclase-activating polypeptide receptor activity
transmembrane signaling receptor activity
G-protein coupled receptor activity
vasoactive intestinal polypeptide receptor activity
G-protein coupled peptide receptor activity
peptide hormone binding
signal transducer activity
transmembrane signal receptor
signal transduction
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
cell-cell signaling
activation of adenylate cyclase activity
negative regulation of smooth muscle cell proliferation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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