Novel Psychoactive Substances

Identifying new psychoactive drugs

The continued emergence of novel psychoactive substances (NPS) poses a number of analytical challenges for forensic laboratories. This category of compounds is differentiated from traditional drugs of abuse by having similar mind-altering properties but different chemical structures, thereby avoiding detection by routine targeted mass spectrometry (MS) screening, and acquiring the misnomer “legal highs”.

The problem for law enforcement is that as soon as an NPS is identified by crime labs and outlawed by the authorities, illicit drug makers are quick to synthesize a new one to take its place. The list of NPS are growing at an alarming rate with as many as 1-2 new compounds hitting the streets  each week, according to the European Drug Monitoring Centre. These drugs include synthetic cannabinoids which function similarly as plant-based THC, piperazines and cathinones which mimick conventional amphetamine and MDMA (ecstasy), and other classes of drugs.

Innovations such as online sample preparation and MS methods that allow easy retrospective analysis are improving casework backlog.

Learn about the latest advances in chromatography and MS solutions from Thermo Scientific for confidently identifying NPS, including state-of-the-art high-resolution accurate mass (HRAM) MS Orbitrap technology for reliable screening and confirmation in a single run.

We hope to enable forensic drug testing labs to identify rapidly evolving novel psychoactive drugs faster, and capture traces of tomorrow's drugs today.

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Novel psychoactive substances analysis features


Application - The product is For General Lab Use Only - Not For Diagnostic Procedures

Our General Purpose product-lines are not intended for in vitro diagnostic purposes in accordance with our product documentation, manuals, and labels. They are designated for General Laboratory Use Only.

Our Products have not been tested or validated for such applications and their use for in vitro diagnostic purposes may result in inaccurate results and, more seriously, health and safety risks.

 

The product is For General Lab Use Only - Not For Diagnostic Procedures. The application is For Research Use Only. Not for use in diagnostic procedures.