High-Resolution Accurate-Mass MS/MS Spectral Libraries

Library of Toxicological Compounds

• Over 900 unique compounds of interest to the clinical research and forensic toxicology communities:
  • Compound Class and Number of Compounds:
    • Prescription drugs: 612 compounds
    • Natural and industrial toxins: 205 compounds
    • Drugs of abuse: 62 compounds
    • Drugs of interest for monitoring research: 30 compounds
    • Performance enhancing drugs: 13 compounds
• Five to six HRAM MS/MS spectra per compound
• Updatable from the ever-growing mzCloud™ online repository of compounds
• Can be customized by adding proprietary and laboratory-specific compounds and spectra
• The libraries are fully integrated with, and searchable using, TraceFinder and ToxFinder software

Library of Food Safety and Environmental Compounds

• More than 1600 unique compounds of interest to the food safety and environmental testing communities:
  • Compound Class and Number of Compounds:
    • Pesticides: 698 compounds
    • Emerging contaminants: 756 compounds
    • Veterinary drugs: 108 compounds
    • Mycotoxins: 44 compounds
    • PFCs: 21 compounds
• Five to six HRAM MS/MS spectra per compound
• Updatable from the ever-growing mzCloud™ online repository of compounds
• Can be customized by adding proprietary and laboratory-specific compounds and spectra
• The libraries are fully integrated with, and searchable using, TraceFinder and ToxFinder software

Superb Spectra Quality

• High-resolution spectra minimize false positives, false negatives, and matrix interferences, enhancing confidence in identification of known and unknown compounds
• HRAM MS/MS spectra are collected at 140,000 (FWHM) resolution at m/z 200 using the Thermo Scientific™ Q Exactive™ hybrid quadrupole-Orbitrap™ mass spectrometer
• High-resolution results in baseline separation of 13C, 15N, 18O and 34S isotopes
• HRAM MS/MS spectra are collected at multiple collision energies, maximizing the probability of a hit regardless of the mass spectrometer method

Retention Times for Easier Method Development and Greater Confidence

• The HRAM MS/MS compound database includes retention times (RT's) and relative retention times (RRT's) determined using readily available internal standards
• Retention times simplify method development and increases confidence in compounds detected when performing screening and quantitation
• Multiple column chemistries (C18, PFP, phenyl hexyl) are represented