The Value of MMDx in Diagnostic Uncertainty for Patients with Heart Transplantation: A Case-Based Presentation
Heart transplant patients often have scenarios where in the clinical presentation and pathological diagnosis on biopsy are discrepant. We will explore the utility of MMDx® Heart in such patients through a case-based discussion. This webinar will identify the types of scenarios where gene expression profiling is useful for assessing risk of injury or rejection and will discuss the clinical application in follow-up testing.
Learning objectives:
- Identify scenarios wherein MMDx Heart could be useful
- Introduction to diagnostic reporting of MMDx Heart and their interpretation as relevant to clinical presentation
- Utility of follow-up testing in MMDx Heart
Meet the Speaker
To view the speaker's bio, click on the image.
Ashrith Guha
Ashrith Guha, MD, MPH, FACC | Houston Methodist Hospital – Houston, TX USA
- Medical Director, Mechanical Circulatory Support and Heart Transplant Program
- Director, Pulmonary Hypertension and Right Heart Failure Program (MDHAVC)
- Co-Director, Houston Methodist Hospital CTEPH Program
- Assistant Professor of Cardiology, Houston Methodist Institute for Academic Medicine
- Assistant Professor of Medicine, Weill Cornell Medical College
- Advanced Heart Failure and Transplant Cardiology
Dr. Guha is cardiologist with a specialization in the care of patients with advanced heart failure, mechanical circulatory support, cardiac transplants, and pulmonary hypertension. He received his medical degree from St. John's Medical College in India. He moved to Birmingham, Alabama where he completed a Master’s in Public Health with specialization in Epidemiology. Dr. Guha completed his residency at the University of Texas Medical School in Houston. He continued at the University of Texas Medical School as an assistant professor in the Department of Internal medicine. He subsequently completed his cardiology and advanced heart failure fellowship at the University of Iowa during which he was served as the chief fellow.
He is currently the Medical Director of Mechanical Circulatory Support and Heart Transplant Program and Director of Pulmonary Hypertension and Right Heart Failure Program. His transplant clinical research interest includes immunosuppression, desensitization therapies, and novel diagnostics in allograft rejection . He also oversees a basic science laboratory which studies the role of alternate polyadenylation in development of right ventricular failure in RV pressure overload animal models. He is PI on numerous ongoing clinical trials that involve heart failure, post-transplant survival, and the CardioMEMS HF system.
Ashrith Guha, MD, MPH, FACC
Houston Methodist Hospital
Houston, TX, USA
