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Helping you build better patient profiles in all phases of transplantation
Create your personalized experience
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Trending Topics
Publication Summary
PubSummary | Long Term Survival after Kidney Transplantation
Long-term kidney transplant graft and patient survival have consistently improved with time. Much of the gain is attributed to a superior understanding of pre-transplant immunological risk. Making further gains in graft and patient survival depends upon a holistic approach to reduce causes of graft loss and death.
Publication Summary
PubSummary | Intensity of de novo DSA detected by Immucor Lifecodes assay and C3d fixing antibodies are not predictive of subclinical ABMR after kidney transplantation
In this study on patients from nine French transplant centers, Bertrand et al. demonstrate that there are significant differences between HLA antibody test vendors inability to detect dnDSA in cases of biopsy-proven sABMR.
Community Spotlight
Transforming Diagnostics for Tissue Transplantation
When patients in Saskatchewan need a transplant, they will have their diagnostic testing needs met by the Histocompatibility and Immunogenetics Lab (HIL) at St. Paul’s Hospital in Saskatoon within the Saskatchewan Health Authority.
White Paper
White Paper | Research suggests HLA & HNA may play a critical role in COVID-19 Susceptibility, Immune Protection and Success of Novel Treatments during a Global Pandemic Crisis
We have the requisite HLA and HNA antibody screening products to protect patients from an adverse transfusion-related lung injury during upcoming convalescent plasma therapy trials.
Patient Advocacy
The Painted Turtle Helps Support Renal and Transplant Families
We’ve partnered with The Painted Turtle to support initiatives for renal and transplant families, and we hope you’ll do the same!
Publication Summary
PubSummary | A 2020 Banff Antibody Mediated Injury Working Group examination of international practices for diagnosing antibody mediated rejection in kidney transplantation
Biopsy data is accompanied by DSA data in +/- 30% of cases, suggesting urgent action to improve the accessibility of DSA information is needed.
Publication Summary
PubSummary | Analysis of RNA Transcripts by the Molecular Microscope Diagnostic System Can Direct Management after Indication Kidney Transplant Biopsy
These two cases describe how MMDx was used to aid the management of two patients with Banff diagnoses of “borderline” and “Banff 1a TCMR.”
Community Spotlight
Paving the Way for SARS-CoV-2 Revelations
At Leipzig University Hospital, a strange COVID-19 case has puzzled the immunology research team. In a family of five exposed to the virus, both parents and two female children tested positive.
Publication Summary
PubSummary | Gene Expression Profiling for the Identification and Classification of Antibody-Mediated Heart Rejection
The study describes the molecular landscape of antibody mediated rejection.
Mar
07
Submit HLA Case Study
Upcoming Event
36th Annual HLA & Transplant Workshop
Have a compelling HLA Case Study? Submit your entry and if chosen, you could present at this workshop. Why attend? Explore diversity and equity in transplantation access, successes on paired and living donor programs, and managing highly sensitized patients.
Dec
09
Upcoming Event
2021 CO ACC Heart Failure Summit
This is a regional conference where clinical cardiologists can collaborate and share ideas to ultimately improve the overall care of patients with heart failure.
Recorded Event
Video: Clinical Applications for MMDx®: Gene Expression Profiling in Transplant Biopsies
Dr. Georg Böhmig presents MMDx-Kidney and MMDx-Heart case studies where molecular assessment was applied to diagnose allograft dysfunction and to determine if rejection was due to ABMR, TCMR, or a combination of both.
CEC
Webinar
Recorded Event
Video: Are Dilutions the Solution? Identifying the True Extent of Patient Sensitization
Drs. Mark Stegall and Anat Tambur discuss how serial dilutions of the LABScreen™ Single Antigen assay aid in the assessment of alloantibody levels.
Recorded Event
Video: The Quest for Better Kidney Care in Multicultural Communities
Carolyn of Kidneys Quest Foundation discusses the challenges of dialysis patient care in diverse and underserved communities.
CEC
Recorded Event
Video: Immune Response to COVID-19 and Vaccination in Transplant Patients
The COVID-19 pandemic has impacted the transplant community disproportionately and remains an important topic in the field of histocompatibility and immunology.
Featured Products & Services
Antibody Detection & Monitoring
LABScreen Single Antigen ExPlex Assay
Our LABScreen™ ExPlex assay provides cutting-edge capabilities with a total of 151 Class I and 119 Class II CWD alleles.
HLA Typing
AllType FASTplex NGS Assay
Our AllType™ FASTplex™ assay offers a complete NGS solution that delivers high-resolution genotyping results.
Antibody Detection & Monitoring
LABScreen Autoantibody Assay
This test characterizes and monitors a broad range of biomarker targets in human sera including vimentin, tubulin, and perlecan (LG3).
Transfusion
Blood Genotyping: Blood typing of ABO, RBC, and HPA
Our real-time PCR genotyping assays automate ABO, RBC, and HPA molecular typing, increasing productivity and turnaround time.
Antibody Detection
LABScreen COVID Plus Assay
This multiplex semi-quantitative assay can simultaneously detect the presence of 5 SARS-CoV-2 targets: spike, S1, S2, receptor-binding domain, and nucleocapsid fragments.
Post-transplant
MMDx: Transplant Biopsy Assessment
MMDx®-Heart and MMDx®-Kidney complement conventional biopsy processing to improve the assessment of rejection and injury in transplanted organs.
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