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NeoBiotechnologies
Cadherin 17/LI Cadherin (Liver-Intestine Marker) Recombinant Mouse Monoclonal Antibody (rCDH17/9677)
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Product Details
1015-MSM18-P1ABX
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b, kappa
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
rCDH17/9677
Immunogen
Recombinant fragment (around aa 242-418) of human Cadherin 17 protein (CDH17).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Positive Control:Human stomach, colon, liver or small intestine. HepG2 or HT29 cells.
Cellular Location: Cell Surface. Cytoplasm.
Target Information
CDH17 gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cadherin; cadherin 17, LI cadherin (liver-intestine); cadherin-16; Cadherin-17; FLJ26931; HPT-1 cadherin; human intestinal peptide-associated transporter HPT-1; human peptide transporter 1; Intestinal peptide-associated transporter HPT-1; LI cadherin; LI-cadherin; Liver-intestine cadherin; MGC138218; MGC142024; unnamed protein product
Gene Aliases: CDH16; CDH17; HPT-1; HPT1
UniProt ID: (Human) Q12864
Entrez Gene ID: (Human) 1015
cell morphogenesis
germinal center B cell differentiation
marginal zone B cell differentiation
oligopeptide transport
cell-cell junction assembly
cell adhesion
homophilic cell adhesion via plasma membrane adhesion molecules
integrin-mediated signaling pathway
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
cell migration
B cell differentiation
positive regulation of integrin activation by cell surface receptor linked signal transduction
adherens junction organization
oligopeptide transmembrane transport
cell-cell adhesion mediated by cadherin
spleen development
cell-cell adhesion
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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