Search
Proteintech
MYD88 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
23230-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human,
Monkey,
Mouse,
Rat,
Sheep
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MYD88 Fusion Protein Ag19770 (1-150 aa encoded by BC013589)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Amount
34.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAAGGPGAG SAAPVSSTSS LPLAALNMRV RRRLSLFLNV RTQVAADWTA LAEEMDFEYL EIRQLETQAD PTGRLLDAWQ GRPGASVGRL LELLTKLGRD DVLLELGPSI EEDCQKYILK QQQEEAEKPL QVAAVDSSVP RTAELAGITT L (1-150 aa encoded by BC013589)
Target Information
Myeloid differentiation Marker 88 (MyD88) is an adaptor molecule for the Toll/IL-1R and is involved in the inflammatory response induced by IL-1, IL-18 and LPS. MyD88 recruits IRAK to IL-1 receptor complex in response to IL-1. This pathway further leads to activation of NF-kB. MyD88 has a wide tissue distribution.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: mutant myeloid differentiation primary response 88; myeloid differentiation primary response 88; myeloid differentiation primary response gene (88); Myeloid differentiation primary response protein MyD88; myleoid differentiation primary response protein; TLR adaptor MYD88; unnamed protein product
Gene Aliases: IMD68; MYD88; MYD88D; WM1
UniProt ID: (Human) Q99836
Entrez Gene ID: (Human) 4615
response to molecule of fungal origin
leukocyte activation involved in inflammatory response
neutrophil activation involved in immune response
immune system process
MyD88-dependent toll-like receptor signaling pathway
chromatin organization
chromatin remodeling
phagocytosis
apoptotic process
inflammatory response
signal transduction
cell surface receptor signaling pathway
JNK cascade
Toll signaling pathway
response to virus
induced systemic resistance
gene expression
regulation of gene expression
positive regulation of gene expression
microglia differentiation
response to amine
immunoglobulin mediated immune response
cytokine-mediated signaling pathway
neurogenesis
lipopolysaccharide-mediated signaling pathway
positive regulation of type I interferon production
response to peptidoglycan
response to lipopolysaccharide
regulation of interleukin-6 production
regulation of tumor necrosis factor production
positive regulation of chemokine production
positive regulation of interleukin-1 beta production
positive regulation of interleukin-17 production
positive regulation of interleukin-23 production
positive regulation of interleukin-6 production
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
toll-like receptor 4 signaling pathway
regulation of toll-like receptor 4 signaling pathway
toll-like receptor 5 signaling pathway
toll-like receptor 8 signaling pathway
NIK/NF-kappaB signaling
toll-like receptor TLR6:TLR2 signaling pathway
interleukin-33-mediated signaling pathway
regulation of cell proliferation
defense response to bacterium
defense response to protozoan
positive regulation of I-kappaB kinase/NF-kappaB signaling
response to amino acid
skin development
innate immune response
response to ethanol
positive regulation of transcription from RNA polymerase II promoter
positive regulation of JNK cascade
positive regulation of smooth muscle cell proliferation
positive regulation of lymphocyte proliferation
regulation of inflammatory response
defense response to Gram-positive bacterium
positive regulation of NF-kappaB transcription factor activity
defense response to virus
type I interferon signaling pathway
positive regulation of macrophage cytokine production
interleukin-1-mediated signaling pathway
response to interleukin-1
3'-UTR-mediated mRNA stabilization
neutrophil mediated killing of bacterium
cellular response to lipopolysaccharide
cellular response to mechanical stimulus
establishment of endothelial intestinal barrier
cellular response to oxidised low-density lipoprotein particle stimulus
positive regulation of cytokine production involved in inflammatory response
positive regulation of NLRP3 inflammasome complex assembly
regulation of neutrophil migration
regulation of chemokine (C-X-C motif) ligand 1 production
regulation of chemokine (C-X-C motif) ligand 2 production
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support