Bz-rA CEP is a phosphoramidite containing 5' DMT and the nucleoside adenosine (A) with Benzoyl (Bz) base protection, for use in oligonucleotide synthesis. RNA phosphoramidites contain a 2'-OH protecting group, tBDMS (tert-butyl dimethylsilyl). Each base has unique protecting groups designed specifically to protect the RNA during the chemical synthesis process, and produce the highest amount of full length product. Alternate base protection options are also available to allow for faster deprotection and longer oligonucleotide synthesis. The 'Standard Grade' marking denotes a baseline level of purity verified with analytical methods, and proven to be suitable for most oligo synthesis requirements. This product is supplied in a 60 mL Amber bottle with a Serum Vial neck style, which is compatible with most ABI Systems|AKTA Systems of oligonucleotide synthesizers.
• Full chemical name—5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-O-TBDMSi-adenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
• Molecular formula—C53H66N7O8PSi
• Base Protection—Bz
• Formula weight—988.2 g/mol
• CAS number—104992-55-4
• HPLC Purity—≥98.0%
• 31P NMR Purity—≥98.0%; Sum of non-primary peaks in 140-152 ppm range: ≤0.5%