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Invitrogen
PEBP1 Polyclonal Antibody
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FIGURE: 1 / 7
PEBP1 Antibody (36-0700) in ICC/IF
Immunofluorescence analysis of RKIP (N-term) was performed using 70% confluent log phase Hep G2 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with PEBP1 Rabbit Polyclonal Antibody (Product # 36-0700) at 2µg/mL in 0.1% BSA and incubated for 3 hours at room temperature and then labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Pro... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
36-0700
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Dog,
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide derived from the N-terminal region of human RKIP (Raf kinase inhibitor protein).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.25 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.1% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
PBP binds ATP, opioids and phosphatidylethanolamine, exhibiting a lower affinity for phosphatidylinositol and phosphatidylcholine. This serine protease inhibitor inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase. PBP contains hippocampal cholinergic neurostimulating peptide (HCNP), which may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the production of choline acetyltransferase but not acetylcholinesterase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 23 kDa morphine-binding protein; epididymis luminal protein 210; epididymis secretory protein Li 34; epididymis secretory protein Li 96; HCNPpp; hippocampal cholinergic neurostimulating peptide; KIAA0299; LDGF; MDGF; MOCA; neuropolypeptide h3; P23K; PEBP; PEBP-1; PPBP; prostatic binding protein; raf kinase inhibitor protein; Raf kinase inhibitory protein; Raf-1 inhibitor protein; Raf-1 kinase inhibitor protein; unnamed protein product
Gene Aliases: HCNP; HCNPpp; HEL-210; HEL-S-34; HEL-S-96; PBP; Pbp1; Pbpr; PEBP; PEBP-1; RKIP
UniProt ID: (Human) P30086, (Rat) P31044, (Mouse) P70296
Entrez Gene ID: (Human) 5037, (Rat) 29542, (Mouse) 23980
MAPK cascade
negative regulation of protein phosphorylation
regulation of the force of heart contraction
response to oxidative stress
spermatid development
response to xenobiotic stimulus
response to toxic substance
response to activity
hippocampus development
eating behavior
negative regulation of MAPK cascade
response to ethanol
positive regulation of mitotic nuclear division
sperm capacitation
response to corticosterone
response to cAMP
response to calcium ion
response to electrical stimulus
positive regulation of acetylcholine metabolic process
positive regulation of cAMP/PKA signal transduction
positive regulation of acetylcholine biosynthetic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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