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Proteintech
PAK1 Polyclonal Antibody
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Product Details
51137-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Amount
19.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Target Information
PAK1 is a serine/threonine kinase that is a target for restenosis, cancer, and immunosuppression treatment. These proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK1 regulates cell motility and morphology.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ADRB2; alpha pak; Alpha-PAK; EC 2.7.11.1; kinase PAK1; MGC130000; MGC130001; p21 protein (Cdc42/Rac)-activated kinase 1; p21-activated kinase 1; p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast); p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related); p65-PAK; PAK 1; PAK-1; PAK1B; protein kinase; Serine/threonine-protein kinase PAK 1; STE20 homolog, yeast; unnamed protein product
Gene Aliases: alpha-PAK; IDDMSSD; p65-PAK; PAK1; PAKalpha
UniProt ID: (Human) Q13153
Entrez Gene ID: (Human) 5058
nucleotide binding
catalytic activity
protein kinase activity
protein serine/threonine kinase activity
protein binding
collagen binding
ATP binding
kinase activity
transferase activity
protein kinase binding
small GTPase binding
identical protein binding
gamma-tubulin binding
protein serine kinase activity
MAPK cascade
response to hypoxia
stimulatory C-type lectin receptor signaling pathway
chromatin remodeling
exocytosis
apoptotic process
cellular response to DNA damage stimulus
transmembrane receptor protein tyrosine kinase signaling pathway
positive regulation of cell proliferation
cellular response to starvation
positive regulation of fibroblast migration
cell migration
cerebellum development
establishment of cell polarity
actin cytoskeleton organization
positive regulation of cell migration
positive regulation of microtubule polymerization
cellular response to insulin stimulus
regulation of actin cytoskeleton organization
positive regulation of intracellular estrogen receptor signaling pathway
intracellular signal transduction
Fc-gamma receptor signaling pathway involved in phagocytosis
wound healing
regulation of MAPK cascade
positive regulation of axon extension
positive regulation of insulin receptor signaling pathway
hepatocyte growth factor receptor signaling pathway
ephrin receptor signaling pathway
branching morphogenesis of an epithelial tube
neuron projection morphogenesis
regulation of axonogenesis
positive regulation of stress fiber assembly
negative regulation of cell proliferation involved in contact inhibition
negative regulation of cell growth involved in cardiac muscle cell development
positive regulation of microtubule nucleation
positive regulation of protein targeting to membrane
regulation of actin filament organization
protein localization to cytoplasmic stress granule
positive regulation of vascular smooth muscle cell proliferation
positive regulation of vascular associated smooth muscle cell migration
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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