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Proteintech
INSRR Polyclonal Antibody
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Product Details
55112-1-AP
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Amount
34.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
The antibody is specific to INSRR.
Target Information
INSRR, insulin receptor-related receptor, is a member of the insulin receptor (IR) family. INSRR does not bind insulin-like molecules, but is similar to INSR in tyrosine kinase activity. Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Insulin receptor-related protein; IR-related receptor; IRR
Gene Aliases: INSRR; IRR; Sirr
UniProt ID: (Human) P14616, (Mouse) Q9WTL4, (Rat) Q64716
Entrez Gene ID: (Human) 3645, (Mouse) 23920, (Rat) 60663
nucleotide binding
protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
insulin-activated receptor activity
protein binding
ATP binding
kinase activity
transferase activity
phosphatidylinositol 3-kinase binding
insulin receptor substrate binding
transferase activity, transferring phosphorus-containing groups
transmembrane signal receptor
transmembrane receptor protein tyrosine kinase signaling pathway
insulin receptor signaling pathway
actin cytoskeleton organization
male sex determination
protein autophosphorylation
cellular response to alkaline pH
protein phosphorylation
signal transduction
phosphorylation
peptidyl-tyrosine phosphorylation
actin cytoskeleton reorganization
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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