Thermo Scientific™

Pharma 16 Twin-Screw Extruder

Catalog number: 553-1040
Thermo Scientific™

Pharma 16 Twin-Screw Extruder

Catalog number: 553-1040
Rapidly develop pharmaceutical formulations and adopt continuous processing methods using the Thermo Scientific™ Pharma 16 Twin-Screw Extruder.  The Pharma 16 Twin-Screw Extruder can switch between continuous hot melt extrusion (HME) or wet granulation (TSG) with ease. Optimize drug process development parameters with less time and effort than batch processes and easily scale-up to larger Thermo Scientific™ extruders with using minimal amounts of expensive APIs and excipients. 
 
Catalog Number
553-1040
Unit Size
Each
Description
Pharma 16 Twin-Screw Extruder
Price (USD)
Full specifications
Max. Speed1000 rpm
Speed Range10 to 1000 rpm
Electrical Requirements400 V 3Ph +N + PE (± 10%)
IP RatingIP 54
Pressure150 bar
ThroughputHME: 0.5-5 kg/h / TSG: 1-15 kg/h (depending on formulation)
Max. Torque18 Nm/Screw
Barrel Zones7 barrel zones (1st zone permanent cooled) + 1 die heater
Dimensions (L x W x H)1750 x 610 x 1220 mm
Barrel Length L/D40:1 L/D
Length (English)Screw length: HME L/D = 40 (40 x 16 mm = 640 mm), TSG L/D = 40.75 (40.75 x 16 mm = 652 mm)
Temperature Range (Metric)HME: 10 to 300°C, TSG: 10 to 100°C
BarrelBarrel Length 40:1 L/D
7 barrel zones (1st zone permanent cooled) + 1 die heater
Center Line Spacing1050 mm
DescriptionPharma 16 Twin-Screw Extruder
Weight (Metric)350 kg
Unit SizeEach
Showing 1 of 1
Catalog NumberSpecificationsUnit SizeDescriptionPrice (USD)
553-1040Full specifications
EachPharma 16 Twin-Screw ExtruderRequest A Quote
Max. Speed1000 rpm
Speed Range10 to 1000 rpm
Electrical Requirements400 V 3Ph +N + PE (± 10%)
IP RatingIP 54
Pressure150 bar
ThroughputHME: 0.5-5 kg/h / TSG: 1-15 kg/h (depending on formulation)
Max. Torque18 Nm/Screw
Barrel Zones7 barrel zones (1st zone permanent cooled) + 1 die heater
Dimensions (L x W x H)1750 x 610 x 1220 mm
Barrel Length L/D40:1 L/D
Length (English)Screw length: HME L/D = 40 (40 x 16 mm = 640 mm), TSG L/D = 40.75 (40.75 x 16 mm = 652 mm)
Temperature Range (Metric)HME: 10 to 300°C, TSG: 10 to 100°C
BarrelBarrel Length 40:1 L/D
7 barrel zones (1st zone permanent cooled) + 1 die heater
Center Line Spacing1050 mm
DescriptionPharma 16 Twin-Screw Extruder
Weight (Metric)350 kg
Unit SizeEach
Showing 1 of 1

The Pharma 16 Twin-Screw Extruder is ideal for pilot-scale, continuous HME or TSG processes used for research, development or production in the pharmaceutical industry. Companies can bring products to market faster and with high quality by developing a continuous process for solid dosage forms compared to a batch process. Effects of pilot-scale process conditions on drug formulations for drug delivery and pharmaceutics can easily be studied using the Pharma 16 Twin-Screw Extruder.    

 

Pharma 16 Twin-Screw Extruder highlights:

  • 2-in-1 process design – quickly disassemble parts for easy cleaning and process switching from HME to TSG.
  • Simple continuous process integration - plug-and-play functionality with upstream and downstream process equipment (e.g., feeders, chill rolls, pelletizers, dryers, etc) simplifies production line design.
  • Less optimization time, cost and effort – extruder process parameters are scaleable to larger Thermo Scientific extruders due to geometric similarity with minimal use of expensive ingredients.