Thermo Scientific™

Pharma 16 Twin-Screw Extruder

Catalog number: 553-1040
Thermo Scientific™

Pharma 16 Twin-Screw Extruder

Catalog number: 553-1040
Rapidly develop pharmaceutical formulations and adopt continuous processing methods using the Thermo Scientific™ Pharma 16 Twin-Screw Extruder.  The Pharma 16 Twin-Screw Extruder can switch between continuous hot melt extrusion (HME) or wet granulation (TSG) with ease. Optimize drug process development parameters with less time and effort than batch processes and easily scale-up to larger Thermo Scientific™ extruders with using minimal amounts of expensive APIs and excipients. 
 
Catalog Number
553-1040
Unit Size
Each
Description
Pharma 16 Twin-Screw Extruder
Price (USD)
Full specifications
BarrelBarrel Length 40:1 L/D
7 barrel zones (1st zone permanent cooled) + 1 die heater
Pressure150 bars (option)
Center Line Spacing1050 mm
Length (English)Screw length: HME L/D = 40 (40x16mm = 640mm)
TSG L/D = 40.75 (40.75x16mm = 652mm)
Speed10-1000 rpm
Temperature (Metric) OperatingHME: 10-300°C / TSG: 10-100°C
ThroughputHME: 0.5-5 kg/h / TSG: 1-15 kg/h (depending on formulation)
DescriptionPharma 16 Twin-Screw Extruder
Max. Torque36 Nm (2 screws, 18 Nm each)
Weight (Metric)350 kg
Power Supply400V 3Ph +N + PE (+/- 10%)
Dimensions (L x W x H)1750mm x 610mm x 1220mm
ProtectionIP 54
Max. Screw Speed1,000 rpm
Unit SizeEach
Showing 1 of 1
Catalog NumberSpecificationsUnit SizeDescriptionPrice (USD)
553-1040Full specifications
EachPharma 16 Twin-Screw ExtruderRequest A Quote
BarrelBarrel Length 40:1 L/D
7 barrel zones (1st zone permanent cooled) + 1 die heater
Pressure150 bars (option)
Center Line Spacing1050 mm
Length (English)Screw length: HME L/D = 40 (40x16mm = 640mm)
TSG L/D = 40.75 (40.75x16mm = 652mm)
Speed10-1000 rpm
Temperature (Metric) OperatingHME: 10-300°C / TSG: 10-100°C
ThroughputHME: 0.5-5 kg/h / TSG: 1-15 kg/h (depending on formulation)
DescriptionPharma 16 Twin-Screw Extruder
Max. Torque36 Nm (2 screws, 18 Nm each)
Weight (Metric)350 kg
Power Supply400V 3Ph +N + PE (+/- 10%)
Dimensions (L x W x H)1750mm x 610mm x 1220mm
ProtectionIP 54
Max. Screw Speed1,000 rpm
Unit SizeEach
Showing 1 of 1

The Pharma 16 Twin-Screw Extruder is ideal for pilot-scale, continuous HME or TSG processes used for research, development or production in the pharmaceutical industry. Companies can bring products to market faster and with high quality by developing a continuous process for solid dosage forms compared to a batch process. Effects of pilot-scale process conditions on drug formulations for drug delivery and pharmaceutics can easily be studied using the Pharma 16 Twin-Screw Extruder.    

 

Pharma 16 Twin-Screw Extruder highlights:

  • 2-in-1 process design – quickly disassemble parts for easy cleaning and process switching from HME to TSG.
  • Simple continuous process integration - plug-and-play functionality with upstream and downstream process equipment (e.g., feeders, chill rolls, pelletizers, dryers, etc) simplifies production line design.
  • Less optimization time, cost and effort – extruder process parameters are scaleable to larger Thermo Scientific extruders due to geometric similarity with minimal use of expensive ingredients.

 

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Frequently asked questions (FAQs)

Citations & References