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NeoBiotechnologies
SSTR2 Monoclonal Antibody (SSTR2/7532)
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Product Details
6752-MSM2-P1
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b, lambda
Class
Monoclonal
Type
Antibody
Clone
SSTR2/7532
Immunogen
Recombinant fragment (around aa300-500) of human SSTR2.
Conjugate
Form
Liquid
Concentration
200 µg/mL
Amount
100 µg
Purification
Protein A/G
Storage buffer
PBS with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Positive Control: colon and liver. Human Cerebrum and kidney. In lesser amounts in jejunum
Cellular Location: Cell surface.
Target Information
SSTR2 (somatostatin receptor 2) is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in the cerebrum and kidney. Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The receptor is coupled via pertussis toxin sensitive G proteins to inhibit adenylyl cyclase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: somatostatin receptor; somatostatin receptor 2a; Somatostatin receptor type 2; SRIF-1; SS-2-R; SS2R; SSR2; SSTR2A; unnamed protein product
Gene Aliases: SST2; SSTR2
UniProt ID: (Human) P30874
Entrez Gene ID: (Human) 6752
signal transduction
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
neuropeptide signaling pathway
negative regulation of cell proliferation
somatostatin signaling pathway
cellular response to glucocorticoid stimulus
cellular response to estradiol stimulus
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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