Search
{{$ctrl.translations['antibody.pdp.skuNotes.additionalInformation'] || 'Additional Information'}}:
{{$ctrl.translations['antibody.pdp.skuNotes.additionalInformation']}}:
FIGURE: 1 / 5
H3K18ac Antibody (703896) in WB
Western blot was performed using H3K18ac Recombinant Rabbit Monoclonal Antibody (Product # 703896) and a 17 kDa band corresponding to H3K18ac was observed across the cell lines tested. Acid extracts (30 µg lysate) of HeLa (Lane 1), NIH/3T3 (Lane 2), Neuro-2a (Lane 3), A549 (Lane 4), HCT 116 (Lane 5), DU 145 (Lane 6), and SK-OV-3 (Lane 7) were electrophoresed using Novex® NuPAGE® 10 % Bis-Tris gel (Product # NP0301BOX). Resolved proteins were then transferred onto a nitrocellulose membrane (Product # IB23001) by iBlot® 2 Dry Blotting System... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
703896
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
Expi293
Class
Recombinant Monoclonal
Type
Antibody
Clone
15H29L63
Immunogen
Peptides corresponding to human H3K18ac [aa15-aa22]
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.2-7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
Product Specific Information
This antibody is predicted to react with Rat and Bovine.
Target Information
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modification that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Acetyl H3; Acetyl Histone H3; Acetyl-H3 K18; Acetyl-H3 Lys18; Acetyl-Histone H3 K18; Acetyl-Histone H3 Lys18; H3; H3 histone; H3 histone family, member A; H3 histone family, member B; H3 histone family, member C; H3 histone family, member D; H3 histone family, member F; H3 histone family, member H; H3 histone family, member I; H3 histone family, member J; H3 histone family, member K; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3 K18; H3 K18ac; H3-clustered histone 13; H3-clustered histone 14; H3-clustered histone 15; H3-clustered histone 2; H3-clustered histone 3; H3-clustered histone 4; H3-clustered histone 6; H3-clustered histone 7; H3/b; H3/d; H3/f; H3/j; H3K18; H3Lys18ac; HIST1H3A; HIST1H3E; HIST1H3F; histone 1, H3a; histone 1, H3b; histone 1, H3c; histone 1, H3d; histone 1, H3e; histone 1, H3f; histone 1, H3g; histone 1, H3h; histone 1, H3i; histone 1, H3j; histone 2, H3a; histone 2, H3c; histone 2, H3c1; histone 2, H3c2; histone 2, H3ca1; histone 2, H3ca2; histone 2, H3d; Histone 3; histone cluster 1 H3 family member a; histone cluster 1 H3 family member b; histone cluster 1 H3 family member c; histone cluster 1 H3 family member d; histone cluster 1 H3 family member e; histone cluster 1 H3 family member f; histone cluster 1 H3 family member g; histone cluster 1 H3 family member h; histone cluster 1 H3 family member i; histone cluster 1 H3 family member j; histone cluster 1, H3a; histone cluster 1, H3b; histone cluster 1, H3c; histone cluster 1, H3d; histone cluster 1, H3e; histone cluster 1, H3f; histone cluster 1, H3g; histone cluster 1, H3h; histone cluster 1, H3i; histone cluster 1, H3j; histone cluster 2 H3 family member a; histone cluster 2 H3 family member c; histone cluster 2 H3 family member d; histone cluster 2, H3a; histone cluster 2, H3b; histone cluster 2, H3c; histone cluster 2, H3c1; histone cluster 2, H3c2, pseudogene; histone cluster 2, H3d; histone gene complex 1; Histone H3; histone H3/a; histone H3/b; histone H3/c; histone H3/d; histone H3/f; histone H3/h; histone H3/i; histone H3/j; histone H3/k; histone H3/l; histone H3/m; histone H3/o; Histone H3K18; Histone H3K18ac; histone protein Hist2h2bb; histone1, H3c; histone1, H3d; unnamed protein product
Gene Aliases: H3; H3-143; H3-291; H3-53; H3-614; H3-615; H3-616; H3-b; H3-f; H3-H; H3.1; H3.1-221; H3.2; H3.2-221; H3.2-614; H3.f; H3/A; H3/b; H3/c; H3/d; H3/f; H3/h; H3/i; H3/j; H3/k; H3/l; H3/M; H3/n; H3/o; H3c1; H3c10; H3c11; H3c13; H3c14; H3c15; H3c2; H3c3; H3c4; H3c6; H3c7; H3c8; H3F1K; H3F2; H3FA; H3FB; H3FC; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; H3FM; H3FN; Hist1; HIST1H3A; HIST1H3B; HIST1H3C; HIST1H3D; HIST1H3E; HIST1H3F; HIST1H3G; HIST1H3H; HIST1H3I; HIST1H3J; HIST2H3A; Hist2h3b; HIST2H3C; Hist2h3c1; Hist2h3c2; Hist2h3c2-ps; Hist2h3ca1; HIST2H3D
UniProt ID: (Human) P68431, (Human) Q71DI3, (Mouse) P68433, (Mouse) P84228
Entrez Gene ID: (Human) 8350, (Human) 8357, (Human) 8354, (Human) 8356, (Human) 653604, (Human) 126961, (Human) 333932, (Human) 8358, (Human) 8352, (Human) 8351, (Human) 8353, (Human) 8968, (Human) 8355, (Mouse) 360198, (Mouse) 319152, (Mouse) 319153, (Mouse) 319154, (Mouse) 15077, (Mouse) 97114, (Mouse) 319150, (Mouse) 319148, (Mouse) 319149, (Mouse) 319151, (Mouse) 260423, (Mouse) 97908
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support